| IUPAC name
| Other names
|Molar mass||74.085 g/mol|
|Boiling point||261 °C (502 °F; 534 K)|
|Solubility||Reacts with acids|
|Safety data sheet||None|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Aminoguanidine, also known as pimagedine, is an organic base, a derivate of guanidine.
Aminoguanidine is highly basic, and will readily absorb carbon dioxide forming aminoguanidine carbonate/bicarbonate.
Aminoguanidine is a white solid.
Pure aminoguanidine is difficult to find, but its salts are more readily available.
Aminoguanidine can be prepared from calcium cyanamide and hydrazine sulfate. Reaction produces impure aminoguanidine, which is then converted to aminoguanidine bicarbonate, for easier purification. To obtain the free base, a strong base, like sodium methoxide is added and the freebase aminoguanidine is extracted.
Aminoguanidine can also be prepared by reducing nitroguanidine with zinc powder in acetic acid. Reaction produces aminoguanidine acetate, which can be converted into pure base by dissolving the solid in another solvent, then adding a strong base, like sodium methoxide.
A better reduction of nitroguanidine can be performed by adding zinc powder to a stirred suspension of nitroguanidine in ammonium sulfate solution. The zinc oxide sludge is filtered off and remaining zinc is kept dissolved by adding ammonia solution, the aminoguanidine is precipitated as the bicarbonate.
- Make aminoguanidinium nitrate
- Make tetrazoles
- Make nickel complexes
There is little information about the toxicity of this compound and its salts. Pimagedine, like other guanidine derivates, has been investigated in the treatment of diabetes, more specifically diabetic kidney disease.
In closed bottles.
No special disposal is required. Can be poured down the drain.