| IUPAC name
| Other names
|Molar mass||128.94 g/mol|
|Density||1.5634 g/cm3 (20 °C)|
|Melting point||13.5 °C (56.3 °F; 286.6 K)|
|Boiling point||194 °C (381 °F; 467 K)|
|Solubility|| Miscible with acetone, alcohols, diethyl ether|
Slightly soluble in carbon tetrachloride
|Vapor pressure||0.142 mmHg at 20 °C|
Std enthalpy of
|Safety data sheet||Sigma-Aldrich|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|2,820 mg/kg (rat, oral)|
| Acetic acid|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Dichloroacetic acid or DCA, is the chemical compound with formula CHCl2COOH.
As an acid with a pKa of 1.35, pure dichloroacetic acid is quite strong for an organic acid.
Dichloroacetic acid is a colorless liquid, miscible with water. It has a pungent acetic odor.
Dichloroacetic acid is sold by lab suppliers.
DCA has been shown to occur in nature in at least one seaweed, Asparagopsis taxiformis.
Chlorination of glacial acetic acid in the presence of UV light will yield mono-, di- and tri-chloroacetic acids. Separating the components via fractional distillation is difficult but doable with the right equipment.
- Make difluoroacetic acid
- Cosmetic treatments (chemical peels, wart removal)
- Chloroacetic acid poisoning antidote
Dichloroacetic acid is very corrosive and extremely destructive to tissues of the mucous membranes and upper respiratory tract via inhalation.
Dichloroacetic acid should be kept in closed bottles. Since it has a relative high freezing point, it can be stored in a fridge or freezer, where it's less volatile in its solid phase.
Should be strongly diluted before poured down the drain.
Complete reduction with a suitable reducing agent will yield acetic acid, which is non-toxic.