Difluoroacetic acid

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Difluoroacetic acid
Difluoroacetic acid structural formula.png
Names
IUPAC name
2,2-Difluoroethanoic acid
Other names
2,2-Difluoroacetic acid
DFA
Identifiers
Jmol-3D images Image
Properties
C2H2F2O2
CHF2COOH
Molar mass 96.033 g/mol
Appearance Colorless liquid
Odor Odorless
Density 1.526 g/cm3 (at 25 °C)
Melting point −1 °C (30 °F; 272 K)
Boiling point 132–134 °C (270–273 °F; 405–407 K)
Miscible
Solubility Miscible with alcohols
Acidity (pKa) 1.13[1]
Hazards
Safety data sheet Sigma-Aldrich
Flash point 78 °C (172.4 °F; 351 K)
Related compounds
Related compounds
Acetic acid
Fluoroacetic acid
Trifluoroacetic acid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Difluoroacetic acid is a chemical compound with chemical formula CHF2COOH.

Properties

Chemical

Difluoroacetic acid reacts with bases to form the corresponding difluoroacetate salts.

Physical

Difluoroacetic acid is a colorless liquid, miscible with water and alcohols.

Availability

DFA is sold by lab suppliers.

Preparation

Can be prepared by refluxing potassium fluoride with dichloroacetic acid.

Projects

  • Make difluoroacetate salts
  • Compound collecting

Handling

Safety

Difluoroacetic acid is toxic, though less so than its monofluoroacetic derivate. Chronic exposure has been linked to nerve and liver damage.

Storage

In closed bottles, with a PTFE seal and a hazardous chemical label.

Disposal

Should be neutralized with a base. The resulting salts should be taken to waste disposal facilities or recycled.

References

  1. https://www.chem.wisc.edu/areas/reich/pkatable/pKa_compilation-1-Williams.pdf

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