Guanidinium sulfate

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Guanidinium sulfate
Names
IUPAC name
Guanidinium sulfate
Other names
Carbamimidoylammonium sulfate
Carbamimidoylazanium sulfate
Guanidine sulfate
Guanidine, sulfuric acid salt
Properties
C2H12N6O4S
(C(NH2)3)2SO4
Molar mass 216.216 g/mol
Appearance White solid
Odor Odorless
Melting point 290–293 °C (554–559 °F; 563–566 K) (decomposes)
Boiling point Decomposes
Soluble
Solubility Almost insoluble in alcohol
Vapor pressure ~0 mmHg
Hazards
Safety data sheet Sigma-Aldrich
Lethal dose or concentration (LD, LC):
475 mg/kg (rat, oral)[1]
Related compounds
Related compounds
Guanidinium carbonate
Guanidinium chloride
Guanidinium nitrate
Guanidinium perchlorate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Guanidinium sulfate, incorrectly referred to as guanidine sulfate, is a colorless solid with the chemical formula C2H12N6O4S or (C(NH2)3)2SO4, often shorted to (Gdn)2SO4.

Properties

Chemical

Adding calcium nitrate to guanidinium sulfate will give guanidinium nitrate, while calcium sulfate precipitates out of the reaction:

(C(NH2)3)2SO4 + Ca(NO3)2 → 2 C(NH2)3NO3 + CaSO4

Physical

Guanidinium sulfate is a white solid.

Availability

Guanidinium sulfate can be bought from chemical suppliers an online.

Preparation

Can be prepared from the complete neutralization of sulfuric acid with guanidine or guanidinium carbonate.

2 HNC(NH2)2 + H2SO4 → (C(NH2)3)2SO4
(C(NH2)3)2CO3 + H2SO4 → (C(NH2)3)2SO4 + H2O + CO3

A less known route involves fusing urea with ammonium sulfamate in a 1:3 molar ratio. Ammonium sulfate is produced as secondary product.[2]

2 NH4SO3NH2 + 6 (NH2)2CO → (C(NH2)3)2SO4 + NH4SO4 + H2O + CO + N2

Projects

  • Make other guanidinium compounds
  • Make zinc guanidinium sulfate crystals[3]

Handling

Safety

There isn't much info about the toxicity of guanidinium sulfate, though it's best to handle it with care.

Storage

In closed bottles.

Disposal

No special disposal is required.

References

  1. http://www.minclinic.ru/drugs/drugs_eng/G/Guanidinium%20Sulfate.html
  2. https://www.google.com/patents/US2464247
  3. http://scripts.iucr.org/cgi-bin/paper?S0567740870002364

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