| IUPAC name
| Other names
|Molar mass||59.11 g/mol|
|Appearance||Colorless hygroscopic liquid|
|Density||0.6891 g/cm3 (at 20 °C)|
|Melting point||−95.20 °C (−139.36 °F; 177.95 K)|
|Boiling point||32.4 °C (90.3 °F; 305.5 K)|
|Solubility|| Reacts with acids|
Miscible with acetone, benzene, chloroform
|Vapor pressure||63.41 kPa (at 20 °C)|
Std enthalpy of
|Safety data sheet||ScienceLab|
|Flash point||−18 °C (-35 °C by others)|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
| 380 mg/kg (dermal, rabbit)|
550 mg kg−1 (oral, rat)
LC50 (Median concentration)
|4,000 ppm (rat, 4 hr)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Isopropylamine, also known as 2-propanamine or propan-2-amine, is an organic amine compound, mostly used as a solvent. It has the chemical formula C3H9N or (CH3)2CHNH2. While "isopropylamine" can be shortened to "IPA", this is not recommended, as IPA also stands for isopropyl alcohol.
Isopropylamine reacts with acids, such as hydrochloric acid to form isopropylamine salts, such as isopropylamine chloride.
Isopropylamine is a hygroscopic colorless volatile liquid, with a strong fish or ammonia-like odor. It has a low boiling point of only 32.4 °C, while its melting point is −95.2 °C. Isopropylamine is miscible with water, as well as other organic solvents, such as ethanol, diethyl ether. It is also soluble in acetone, benzene, chloroform, but reacts with acidic solvents. It is extremely flammable, with a flash point of -18 °C or −35 °C (according to ESIS) and an autoignition temperature of 402 °C.
Isopropylamine is sold by various chemical suppliers.
Sciencelab sells 500 ml at $85.55.
- Extract natural compounds
- Make N-methylisopropylamine
Isopropylamine has an unpleasant fishy smell, and it poses some toxicity. Skin contact with pure isopropylamine may cause burns. Vapors can severely irritate eyes and lungs.
It is volatile and quite flammable.
Isopropylamine, if desired as free base, must be stored in closed bottles, in dark and well ventilated places. Scrubbers containing low-volatile acids, like oxalic acid can be used to neutralize escaping isopropylamine vapors.
Isopropylamine salts must be stored in closed bottles, away from moisture and acidic vapors.
Isopropylamine can be disposed of by burning it, either pure or mixed with a more volatile solvent. This produces carbon dioxide/monoxide, water vapors and traces of unburnt isopropylamine. The traces will give the smoke a bad smell, so it's recommended you do this in open spaces, away from people, and you should burn small amounts at a time.
Isopropylamine can be destroyed by adding it dropwise in a solution of Fenton's reagent. Since the destruction process will aerosolize a small amount of isopropylamine, this is best done outside. As isopropylamine has a strong and unpleasant smell, do not do this indoors!
Adding an acid to isopropylamine will give off a very fine salt mist.