| IUPAC name
| Systematic IUPAC name
| Other names
|Molar mass||165.189 g/mol|
|Melting point||89 °C (192 °F; 362 K)|
|Boiling point||310 °C (590 °F; 583 K)|
|Solubility|| Very soluble in chloroform, diethyl ether, ethanol|
Soluble in diluted acids
|Safety data sheet||ScienceLab|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Benzocaine is a topical anesthetic that helps to numb the pain and itching. It's used as a topical pain reliever or in cough drops. Benzocaine combined with antipyrine forms A/B otic drops to relieve ear pain and remove earwax.
Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol by Fischer esterification or via the reduction of ethyl p-nitrobenzoate.
Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform and ethyl ether.
Benzocaine is sold in various drugstores.
Benzocaine can be prepared by esterfication using 4-aminobenzoic acid and ethanol. It can also be prepared by reduction of ethyl 4-nitrobenzoate to the amine.
In industrial practice, the reducing agent is usually iron and water in the presence of a little acid.
- Local anesthetic
Do not use benzocaine topical if you have ever had methemoglobinemia in the past.
Benzocaine should be stored in closed bottles, away from moisture and air, if stored for long periods of time.
Benzocaine can be either oxidized with Fenton's reagent or poured down the drain, depending on the amount of waste you intend to dispose.