Low purity forerun (left) and high purity end run (right) tert-amyl alcohol, obtained via Grignard reaction route.
| IUPAC name
| Other names
|Molar mass||88.15 g/mol|
|Density||0.8096 g/cm3 (20 °C)|
|Melting point||−9 °C (16 °F; 264 K)|
|Boiling point||102.4 °C (216.3 °F; 375.5 K)|
|12 g/100 ml|
|Solubility||Miscible with acetone, diethyl ether, benzene, chloroform, ethanol, glycerol, oils|
|Vapor pressure||1.6 kPa (at 20 °C)|
Std enthalpy of
|Safety data sheet||Sigma-Aldrich|
|Flash point||19 °C (66 °F; 292 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|1,000 mg/kg (rat, oral)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
tert-Amyl alcohol, like all tertiary alcohols, is not readily oxidized. Due to the high stability of the tert-amyl cation, it is quite easy to prepare tert-amyl halides by reaction of the alcohol with the corresponding hydrogen halide at room temperature.
tert-Amyl alcohol is a colorless liquid with a camphor-like odor. It is somewhat soluble in water, but miscible with other organic solvents, like alcohols and halocarbons.
tert-Pentanol is sold by chemical suppliers. Can also be bought online.
Can also be extracted via fractional distillation from fusel oil, though you will need large amounts of it.
tert-Amyl alcohol can be prepared via the bromoethylethylmagnesium Grignard with acetone route.
NurdRage has a good video on this process.
tert-Amyl alcohol is flammable and a skin irritant. Ingestion or inhalation produces intoxication similar in many ways to ethanol, though it is around 20 times more potent by volume and produces longer-lasting effects. Exposure to vapor in the lab or accidental ingestion may cause temporary loss of physical and mental faculties or even sedation.
tert-Amyl alcohol should be kept in closed bottles made of glass or chemically resistant plastic such as HDPE, preferably in a flammables cabinet.
Can be safely burned outside. Combustion products are not harmful.