Sciencemadness Discussion Board

Indole Amino alcohols via Akabori

BobHawson - 12-12-2008 at 09:49

I'm sure you all know about the benzaldehyde reaction with alanine to form Phenylpropanolamine.

Here's my question. Do you think Indole-3-carboxaldehyde with alanine would yield Indole-3-propanolamine?

Would the aldehyde react with glycine to give indole-3-ethanolamine?

I assume it would, but I couldn't find anything regarding indole aldehydes in the akabori reaction. There also could be side reactions I'm not taking into account.