Sciencemadness Discussion Board

Pharmaceuticals synthesis

ChemistryForever - 4-1-2019 at 06:14

Where can I find a website with the most common medicines used and their synthesis ( experimental procedures ) ?

j_sum1 - 4-1-2019 at 07:45

Here's your list:
https://en.m.wikipedia.org/wiki/WHO_Model_List_of_Essential_...

You will have to find the synths individually.

AvBaeyer - 4-1-2019 at 19:51

There does not exist any lab manual or cookbook for making common drugs. The Merck Index lists most if not all common drugs with references to their syntheses. Used copies of this are easily found. Also extremely useful if you can find it is the multi-volume Dictionary of Pharmacological Compounds. It is loaded with chemical data and references. Finally, and perhaps most useful, is a hard to find (and expensive) 2 volume set called Pharmaceutical Substances which is a compilation of synthesis routes for most drugs. The ABE booksellers site is a good source for many used scientific books at good prices.

As an aside, most synthesis procedures will be found in the patent literature which often needs a fair amount of "interpretation."

AvB

zed - 5-1-2019 at 15:24

Somewhere in my vast labyrinth of books, I have a copy of Gilmann's.

The way I remember it, it is chocked full of Drugs... Often with Synthesis information.

https://www.amazon.com/Goodman-Gilmans-Pharmacological-Thera...

An expensive buy, for a current edition. Cheaper of course, for an old beater.

Perhaps you can peruse a copy to ascertain its usefulness to you.

WangleSpong5000 - 2-3-2019 at 16:18

Learn chemistry. If you understand first principles than hypothetically you can make anything.

Waffles SS - 2-3-2019 at 23:07

This is good book that i translated into my country language.i always read it

Synthesis of Essential Drugs
Ruben Vardanyan Victor Hruby
https://www.elsevier.com/books/synthesis-of-essential-drugs/...



[Edited on 3-3-2019 by Waffles SS]

Corrosive Joeseph - 2-3-2019 at 23:15

Take yer pick............


Quote: Originally posted by zed  

https://www.amazon.com/Goodman-Gilmans-Pharmacological-Thera...


http://libgen.io/search.php?req=Goodman+and+Gilman%27s+The+P...


Quote: Originally posted by Waffles SS  

Synthesis of Essential Drugs
Ruben Vardanyan Victor Hruby
https://www.elsevier.com/books/synthesis-of-essential-drugs/...


http://libgen.io/search.php?req=Synthesis+of+Essential+Drugs...



/CJ