Sciencemadness Discussion Board

Boronic acids

ChemistryForever - 2-2-2019 at 16:18

Where can I find some literature papers that show how to make these acids? I want to do some Suzuki couplings ...
I cannot find very fancy stuff on prep chem in terms of reactions that would require exotic things such as palladium ...

JnPS - 2-2-2019 at 20:23

There's an ACS review on boron compounds that contains a section on boronic acids. That might be a good place to start looking for a route/procedure: https://pubs.acs.org/doi/abs/10.1021/cr50011a002

I can retrieve the pdf if you need it.

chemister2015 - 4-2-2019 at 01:26

RMgBr + B(OR)3 --> RB(OR)2 + ROMgBr