There was a thread on here discussing whether Hoffman made LSD before it was actually synthesized, thereby getting dosed before actually coming into
contact with the LSD.
David Nichols talked about this, he was convinced that Hoffman got high on LSD without consuming the stuff in the flask and without knowing even
what's in it the first time around, in fact he discovered LSD-25 through some mystical force that in and of itself got him high without consuming the
LSD, I call this force the Light. He must have been very full of this Light and it guided him to the LSD-25.
THERE WAS NO POSSIBILITY OF CONTAMINATION, we are talking BIO LEVEL 4 facility here, the Swiss and Germans are very strict and pedantic about
contamination.
HOLY MARY MOTHER OF GOD!!!!! THIS IS TRUE! It happened again!
[Edited on 15-2-2019 by beerwiz]Sigmatropic - 15-2-2019 at 13:06
No reference, I call bullshit.
This has been suggested before, that the high experienced by hoffmann was a neurological fluke. Mainly propagated by nick sands claiming LSD has low
to no bioavailability when applied topically. I doubt this then (in that thread) and now.
While I certainly believe in nocebo effects when you are working with high potency active pharmaceutical ingredients (or other high potency
compounds). I for one got chills when I was rotavapping down some dozen grams of a material which may have therapeutic effect at 1-2 mg and a
biological half life of 60 hours. Half 'n hour later, I was OK again.
But I doubt one can get it when your working with something your assuming as only moderately potent, unless it is a real effect.
Then again Hoffman did a retest, and it was positive. Further disproving the event was a neurological fluke or nocebo/placebo effectTsjerk - 15-2-2019 at 13:17
I'm positive Sands might have been high when coming up with this. beerwiz - 15-2-2019 at 14:14
[Edited on 15-2-2019 by beerwiz]clearly_not_atara - 15-2-2019 at 16:52
It's important to remember that Hofmann, unlike later LSD experimenters, had no reason to expect the insane potency of the compound he was working
with, and had no limitations on the amount of ergolines he was able to obtain or possess. A tiny amount of the compound that might be ignored and even
worth ignoring if it were something like chloroform could have gotten onto his hands and from there to his face or his food. Heating the freebase
could even result in inhaling some LSD vapor. Or the amount spilled on the skin could have been ridiculous, to the tune of say 100 mg.
[Edited on 16-2-2019 by clearly_not_atara]draculic acid69 - 15-2-2019 at 19:33
Do u really think that in 1932 there was such thing as OHS and safety guidelines. "Excuse me sir would you like to buy a kilo of isopropylbromide"will
give you an idea of what it was like working in a lab back then. level 4 biohazard facility, Nicholas sands,tried it b4 he actually invented it, .
Put the bong down dude.total jibberish.this is the sort of thing that makes sense when you're stoned or on lsd but not when your sober.zed - 16-2-2019 at 17:35
[Edited on 17-2-2019 by zed]beerwiz - 16-2-2019 at 17:39
You are all missing the point. David Nichols was right!
It would be of great value for all on this forum to read this thread carefully from beginning to end. This is the biggest discovery anyone has ever
made or will ever make.zed - 16-2-2019 at 17:47
Beerwiz, I agree.
In fact, I believe you might be high on LSD right now.
Even if you haven't taken any.
Errrr. Are you located somewhere in Russia?draculic acid69 - 16-2-2019 at 22:48
In fact, I believe you might be high on LSD right now.
Even if you haven't taken any.
I agree youre definitely on lsd.even if you didn't take any.
unionised - 17-2-2019 at 09:14
I quite like the irony.
The OP claims that Hoffman was using LSD before it was invented.
He also claims that Hoffman was using BSL4 containment before it was invented.
But somehow, he only thinks that one of the bits of time-travel is important.Elrik - 17-2-2019 at 11:14
Perhaps LSD still hasn't been invented and this is all a hallucination transmitted from the future through quartz crystals?
That seems too mundane an explanation. Perhaps all of human history is a hallucination by a schizophrenic shaman of the dolphin people, brought on by
a pod of datura seeds washed into the ocean by a meteorite impact that narrowly missed hitting a pterodactyl that was contemplating its place in the
universe.
Or, perhaps, you should share some of what ever the hell you're on j_sum1 - 17-2-2019 at 11:21
I don't think this is OC. I am moving it to Miscellaneous. And that is being generous.zed - 17-2-2019 at 15:16
Too generous.
I was hoping a massive "cat fight" would break out.
Thereby sending this pathetic thread to detritus, where it truly belongs.SWIM - 17-2-2019 at 16:22
I wish I could help you out Zed, but I'm just not feeling as fractious as usual today.
I'm afraid the best I could muster would be a hearty, " Sez you!"
But getting high before the drug is synthesized kind of reminds me of the illegal drug in the novel RED DWARF, which is so powerful you can get
addicted to it by just looking at the baggy it's in.
And I believe Schulgin once made a joke about some theoretical compound that if adding each carbon atom to an alkyl group doubled the potency then
just add 80 carbons and you'll get a compound so potent that maybe just drawing the formula would get you high.
That joke is likely about MEM, or EMM, which are mescaline derivatives with a longer alkyl group.
I'd bet MEM, as #4 is usually where the action is on 3,4,5 substituted compounds.
