Around 7 months ago I tried to produce vanillyl amine from capsaicin. That ended badly because I had trouble finding a good source of capsaicin. Then
I got a position as a chemist and stopped home chemistry altogether to focus on work. Now, I want to try that again, having found a good source of
capsaicin powder. However, from the last attempt, I know that my strategy of boiling it in HCl isn't too effective. I was wondering if anyone knew of
any good catalysts for amide hydrolysis. I did see some data about using metal salts to stabilize the tetrahedral intermediate, but pretty must
everything was difficult to obtain triflate salts or Niobium oxide. So does anyone have any experience with mild amide hydrolysis?
|