Sciencemadness Discussion Board

mechanism of sodium dithionite aromatic nitro reduction?

jwarr - 2-6-2022 at 08:12

Hi all,
I'm aware that sodium dithionite can reduce nitrobenzene derivatives to the corresponding aniline. I'm struggling to find a mechanism though? I'd love to see something like an electron pushing diagram showing how the transformation of Ar-NO2 => Ar-NH2. Can someone point me to a reference or perhaps explain it here if it's relatively concise?

Thank you!

Triflic Acid - 2-6-2022 at 08:34

Pretty complex mechanism as far as I could see, uses a sulfur nitrogen bond as the intermediate.

jwarr - 3-6-2022 at 04:41

awesome, thank you!