Sciencemadness Discussion Board

Removal of imidazole (by-product)

Biomaterialist - 25-4-2011 at 03:32

Alló!

I am synthesizing some hydrazines starting with alkyl diols + activation with CDI and then reaction with hydrazide solution. I do this step a few times and the imidazole by-product does not affect my reactions. However, I would like to remove the imidazole for further characterization and I cannot extract it as the final product is also soluble in water.

Any suggestions?