Sciencemadness Discussion Board

Is this a secret chemical, L-serine methyl ester hydrochloride

mentholmadness - 10-1-2013 at 15:05

Well guys i have been looking all over the internet and i cannot source this chemical L-serine methyl ester hydrochloride Nor can i find any synthesis papers.

Only thing i can find is this http://www.sciencedirect.com/science/article/pii/S0022024811...

Does this chemical have a different name ? It's not even found on Wikipedia



[Edited on 10-1-2013 by mentholmadness]

ScienceSquirrel - 10-1-2013 at 15:22

It is reasonably available but not cheap;
http://www.sigmaaldrich.com/catalog/search?interface=Product...
If you want it in serious quantities you should make it from L-serine which is as cheap as chips;
http://www.sigmaaldrich.com/catalog/search?interface=All&...

mentholmadness - 10-1-2013 at 15:26

Wow thanks for the speedy reply,

I see it's avaliable now, But do you think it's avaliable in it's crystalline state

mentholmadness - 10-1-2013 at 20:01

Hmm so how would you get the crystals from L-serine powder form ?

kristofvagyok - 10-1-2013 at 20:47

Quote: Originally posted by mentholmadness  
Hmm so how would you get the crystals from L-serine powder form ?

Recrystallize them from water or some alcohol containing water.

mentholmadness - 10-1-2013 at 21:31

Well i am on a budget and wanting to try this without waiting for shipping times.

Are you saying to dissolve the L-serine powder in water then perform re-crystallization ? If so what type of recrystallization would you use ?.

If so do you think i could use this powder http://www.evidencia-australia.com/p/452006/Musashi-L-Serine...

Would this powder be able to recrystallize into the same as the picture crystal.

Paddywhacker - 10-1-2013 at 22:19

What?

Miscommunication, I think.

If you want crystals of L-serine, then recrystallize it as krysto suggests. If you want the compound you mentioned in your original post then you will first need to esterify the amino acid. Use the search facility for esterification methods.

mentholmadness - 10-1-2013 at 22:26

Oh sorry Paddywhacker,

I want crystals but i am confused because the chemistry paper calls the crystals "Single crystal of l-serine methyl ester hydrochloride (LSMEHCl), was grown using slow evaporation solution growth technique. http://www.sciencedirect.com/science/article/pii/S0022024811...

Which leads me to ask again, Will recrystallizing this powder let me create crystals such as the one in the photo

http://www.evidencia-australia.com/p/452006/Musashi-L-Serine...

mentholmadness - 10-1-2013 at 22:28

So my confusion is that i dont know if L-serine crystals are the same thing as L-serine methyl ester hydrochloride (LSMEHCI) .

kristofvagyok - 10-1-2013 at 22:54

Quote: Originally posted by mentholmadness  
L-serine crystals are the same thing as L-serine methyl ester hydrochloride (LSMEHCI) .

No, they are different things. Serine is an amino acid and serine methyl ester.HCl is an ester of it.

I assume that you only want to get something what is nice and crystalline (based on this and the menthol thread) and it does not matter what is it. So I would recommend to start with inorganics and when inorganic crystallization goes well, then start with easy organics.

http://labphoto.tumblr.com/post/25520946708/this-is-a-time-lapse-video-what-i-made-while-i

mentholmadness - 10-1-2013 at 23:17

Sorry you did not answer my main question.But thankyou very very much in regards to answering all my others


Will 99% Pure L-Serine ( Powder Form ) Recrystallize ? And if so will it stay in its crystalline form in room temp and be able to grow bold crystals ?

If your answer is yes, What recrystallization would you use

[Edited on 11-1-2013 by mentholmadness]

Nicodem - 11-1-2013 at 09:55

First of all learn the basic physical concepts in regard to the melting point. It is obvious from your posts that you don't understand what a melting point is.

http://en.wikipedia.org/wiki/Melting_point

Besides, make up your mind on what exactly you want. L-Serine and L-serine methyl ester hydrochloride are two different compounds!

PS: Open beginner's topics only in the appropriate section and read our forum guidelines for more info.