Sciencemadness Discussion Board

Caffeine

PainKilla - 22-11-2004 at 05:31

Caffeine seems like a pretty cool substance being that it is legal and has similair properties to many illegal substances...though of course I do not want to manufacture any of these these substances, it would definetly be an awesome way to waste some time.

From what I understand caffiene (1,3,7-trimethylxanthine) or C8H10N4O2, affects the adenosine receptors by binding to them inplace of adenosine. This causes the body to panic essentially releasing adrenaline and small amounts of dopamine. This of course, giving you the relaxed yet alert feeling. Since caffeine is such an easy substance to obtain/extract, I am curious if there is any intersting compounds that can be synthesized off of it. Preferably NOT illegal substances. Makes me wonder of what more powerful undiscovered anologues do...

kyanite - 22-11-2004 at 15:05

I think Erowid's vaults have something about this... like analogues or something, where the methyl groups are different.
By the way, caffeine is part of a family called Xanthines. Hope that helps.

unionised - 23-11-2004 at 12:42

I gather that recent work has shown that theobromine, another methylated xanthine, is good at suppressing the cough reflex. (better than codiene)
Bizzarrely, this means that chocolate is good for you.:D

Titan - 31-3-2005 at 06:42

Caffeine,

a bitter substance ?
[low-effect-drug]

Adenosines are a ingredient of the DNA structures. (bases-pairs) ?

sparkgap - 31-3-2005 at 06:45

Yes, it's bitter. Most alkaloids, and in fact, most bases, tend to be bitter-tasting.

Yes, adenosine is a DNA building block.

Yes, your English syntax is freakishly weird. The needle of my troll-detector is kicking a bit...

sparky (^_^)

joe_aldehyde - 31-3-2005 at 08:28

as far as i know, all the xanthines have some pharmacological importance, such as theophylline, theobromine, caffeine, and so on. i have recently made some dervatives of uracil which is a precursor to the xanthines, but i don't know of any xanthines that have the attributes you are looking for. stick to your guarana powder :)

Mr. Wizard - 31-3-2005 at 09:10

Would that be your bot troll detector? I see what you mean.

kyanite - 31-3-2005 at 15:26

Maybe its the_gender_changer!:o

neutrino - 31-3-2005 at 15:31

I doubt it. Too much coherency, not enough emoticons.

Titan - 1-4-2005 at 06:06

sparkgap,

i had looked up for the DNA biochemicals.

Adenosine base-pair :(:( block chemical ;).

Adenin and cytosin DNA or RNA Chemicals.
I`m no a biochemist.

Caffeine - bitter substance (concentreted tasteless) ;).
teeine - bitter substance (concentreted tasteless) ;).

But whats is the caseine ?

sparkgap - 1-4-2005 at 06:15

Titan:

Quote:

Caffeine - bitter substance (concentreted tasteless) .
teeine - bitter substance (concentreted tasteless) .

Eh? What do you wish to speak about now?
Clarify, please. Methinks, however, that the more there is of something, the more potent the taste.

Casein is one of the proteins that comprise milk. It is in no way related to caffeine.

neutrino, he is now using emoticons. My troll-detector needle is still wagging. What do you think?

sparky (^_^)

P.S. If guarana don't work for you, kava might be, shall I say, "your cup of tea". :D

cyclonite4 - 1-4-2005 at 06:35

I'll say he is quite more literate, but still a TGC style idiot. Damn his/her dynamic IP.

I say it's TGC enough...

sparkgap - 1-4-2005 at 06:42

We must admit, however, that TGC set the gold standard for incoherence and inanity here at MSDB. :D

sparky (^_^)

cyclonite4 - 1-4-2005 at 07:07

He practically set a new acronym for stupidity, and various gentic disorders. That acronym is... well, you know. :P

[Edited on 1-4-2005 by cyclonite4]

neutrino - 1-4-2005 at 13:59

I don't know, it's still only two <i>different</i> emoticons. I'd definitely call it a possibility, though.

akinmad - 1-4-2005 at 21:56

I've been here for a long time but this is my second post, I believe.
(My previous post was related to synthesis of creatine).

I have read somewhere Caffeine was hydrolized to sarcosine (an aminoacid) which is a precursor of Creatine synthesis. As you may know the creatine stuff is used for enhancing muscle performance and tonus. Actually it's naturally present in muscle tissues and consumed during muscle activity. HTH.

Edit : My post count shows 9. How can it be? I thought I only posted twice in past :o

[Edited on 2-4-2005 by akinmad]

12AX7 - 2-4-2005 at 00:01

Quote:
Originally posted by akinmad
Edit : My post count shows 9. How can it be? I thought I only posted twice in past :o


Guess not, the FIND button on your post shows the threads...
http://67.15.145.24/~sciencem/talk/misc.php?action=search&srchuname=akinmad&searchsubmit=a&srchfid=all&srchfrom=0

Tim

sparkgap - 2-4-2005 at 06:03

Any references for that, akinmad? I don't see how caffeine can be hydrolyzed into sarcosine.

sparky (^_^)

akinmad - 3-4-2005 at 17:26

IIRC it is hydrolyzed :) into Sarcosine by means of Barium Hydroxide (a nasty compound). However I cannot find any reference for the time being although it is present in my PGP disks. However I found reference for the purin here it is. Whenever I have time I shall attach the file here. But I have more than 10 GB content placed in PGP disks, which makes it cumbersome to find a specific file. (In addition it is 4:30 am in the morning here)

In addition this link which I have difficulty opening it, has some reference that caffeine is synthetically made from sarcosine and cyanamid.

Another link which is actually a PDF file. My bad. The text says caffeine thermally decomposed into sarcosine in presence of barium carbonate not barium hydroxide. :( Please check page 18.

This patent also mentions about thermal decomposition of Caffeine into sarcosine but in presence of Barium hydroxide. HTH.

Weird but I cannot find this patent on US patent office


[Edited on 4-4-2005 by akinmad]

[Edited on 4-4-2005 by akinmad]

sparkgap - 4-4-2005 at 12:12

The reason I was asking was because I haven't encountered hydrolysis reactions for caffeine, but I do seem to recall the thermal decomposition as part of research done in the past. :D Sorry and thanks.

sparky (^_^)