Sciencemadness Discussion Board

Picric Acid ─ not considered harmful . . . ?

hissingnoise - 2-3-2014 at 04:59

This seems a cavalier approach for a chemsupplier in this current milieu?



TheChemiKid - 2-3-2014 at 06:26

What?!

:o

How does the DEA allow this?

Metacelsus - 2-3-2014 at 07:28

It wouldn't be DEA; it would be ATFE.

hissingnoise - 2-3-2014 at 07:31

It's OK, apparently, for an explosive to be high?


DubaiAmateurRocketry - 2-3-2014 at 08:48

Picric acid is sold in most countries as a reagent.

jwpa17 - 2-3-2014 at 16:12

When kept under water, or moist, it IS relatively safe, although the NFPA gives it a 3 for health, and 4's for reactivity and flammability. Biggest problems I know of is that it reacts with metals (like old-fashioned screw cap lids) to make quite unstable picrates and even moist, the material on the threads of any bottle can dry and then is susceptible to explosion due to static.
We used to use it as a peptide fixative in gel electrophoresis - very effective, but the waste disposal issue made me switch to trichloroacetic acid.

The_Davster - 2-3-2014 at 17:02

Quote: Originally posted by jwpa17  
the material on the threads of any bottle can dry and then is susceptible to explosion due to static.


The sensitivity of dry picric acid is low enough that this is not actually a problem.

Cool find.

Chemosynthesis - 2-3-2014 at 19:41

Concerns about mutagenicity would be more founded, in my opinion, though picric acid is a pretty common microscopy staining compound (as evidenced by the link). I remember a lab here had to evacuate a floor of a research facility because an employeee we "let go" had left mounds of the stuff on his bench, among other disgusting waste products. We had no idea how long it had been there, and it was on the chromed faucets as well.

gregxy - 13-3-2014 at 15:38

DNP (2,4 dinitrophenol) can be used for weight loss. It short circuits the electron transport chain. The body responds by burning extra calories to maintain ATP levels. Its like driving a car with your foot halfway on the break.

Users would sweat profusely, and turn yellow. Deaths due to heat exhaustion were quite common so the FDA banned it.
I think dosages were a half a gram or so per day.
Great if you dying to be thin.

http://www.vpxsports.com/article-detail/drugs/dnp-the-most-e...

hissingnoise - 14-3-2014 at 04:53

"Dying" being the operative word here . . .

http://www.sciencemadness.org/talk/viewthread.php?tid=320#pi...