Sciencemadness Discussion Board

Hydrogen sulfide induces artificial hibernation in mice

Quince - 23-4-2005 at 17:08

Room temperature air with 80 ppm HS makes mice hibernate.
http://www.medicalnewstoday.com/medicalnews.php?newsid=23290

Pyridinium - 6-6-2005 at 08:46

That is extremely interesting. I noticed something in there that made me wonder... regarding H2S, they said:

"it's simply an agent that all of us make in our bodies all the time to buffer our metabolic flexibility."

I guess I'd better brush up on my metabolic pathways. I didn't think there was much H2S floating around in our bodies... you know, worse-than-HCN and all...

budullewraagh - 6-6-2005 at 10:29

thats interesting. does anyone know exactly how H2S and HCN inhibit oxidative phosphorylase?

[Edited on 6-6-2005 by budullewraagh]

Pyridinium - 6-6-2005 at 13:08

HCN and H2S both inhibit cytochrome oxidase, which I believe occurs via attack of the heme iron.