Dr.Arz - 14-10-2014 at 10:15
I am trying to synthesize an oxirane soon, but there is one point I am worried about. The synthesis states that the reaction is quenched with little
amount of sodium bisulfite. First, I dont have bisulfite, but instead of sodium dithionite, should this work? Or is it even necessary to do this step,
because the reaction is washed with sodium hydroxide solution, which should neutralize any TCCA or chlorine left in there?
I would also like to know what the quenching actually means, does it play an important role in syntheses?
Chemosynthesis - 14-10-2014 at 10:28
Please post your procedure. There are many ways to go from A to B.
Dr.Arz - 14-10-2014 at 10:53
Oh, I actually found similar synthesis posted to this forum, see this topic about half-way:
http://www.sciencemadness.org/talk/viewthread.php?tid=15284
Chemosynthesis - 16-10-2014 at 04:13
Sometimes reactants need to be quenched to prevent risk of fire or explosion. This can be due to thermal instability or runaway reaction, among
others. I guess you are discussing the peracid methodology? Per acids can form organic peroxides. Adding an ionic solute can also reduce organic vapor
pressure, which may reduce explosion liability.