Sciencemadness Discussion Board

toxin

The_Simpsons - 29-7-2005 at 03:48

does it exist fearinducing chemicals?

sparkgap - 29-7-2005 at 04:16

Ah heck, to answer your "question" (if my understanding of it was correct), search for scotophobin. It's not a toxin, but it is a "fear-inducing" chemical. ;)

sparky (~_~)

[Edited on 29-7-2005 by sparkgap]

12AX7 - 29-7-2005 at 04:20

Add the word "chemical" to it and I'll be damned, everything suddenly induces fear in the average person. Take www.dhmo.org for instance.

Otherwise....you sound like you want mind-altering drugs. All kinds of stuff out there, although I don't know if there are any which specifically induce axiety (anti-valium?).

Oh, and work on your grammar- you meant to say, perhaps, "Do any fear-inducing chemicals exist?"

Tim

The_Simpsons - 29-7-2005 at 04:34

sorry english isn't my first language, and i was in a kind of hurry when i wrote that. the reason i wonder about fearinducing chemicals is just things i've seen in moives and such and i began to wonder if those kind of chemicals really exist

[Edited on 29-7-2005 by The_Simpsons]

sparkgap - 29-7-2005 at 04:38

Oh, sorry then. It's just that the post sounded kind of "k3w1ish", so I was a bit reluctant to answer at first. What good would the answers to this question of yours bring, anyway?

(edit): In that case, I would say now that scotophobin is only effective on mice and fish, AFAIK. I can't really say if a peptide/neurotransmitter in humans plays that role, unless you count in epinephrine which induces the "fight or flight" response in many vertebrates. :)

sparky (~_~)

[Edited on 29-7-2005 by sparkgap]

The_Simpsons - 29-7-2005 at 04:44

im just curious

The_Simpsons - 29-7-2005 at 04:50

plus one of my favorite villain of all times uses that technique, so i began to wonder

12AX7 - 29-7-2005 at 05:57

Quote:
Originally posted by The_Simpsons
plus one of my favorite villain of all times uses that technique, so i began to wonder


Who, Mr. Burns?? :P

The_Simpsons - 29-7-2005 at 06:03

hehe he is one of my favorite simpsons-character, but i ment scarecrow

garage chemist - 29-7-2005 at 06:34

What about Datura (a type of plant, its main toxin is Hyoscyamin)?
All its parts are toxic and it causes real horrortrips as I've heard.

Go to www.erowid.org and look for Datura and then for "experiences".

[Edited on 29-7-2005 by garage chemist]

sparkgap - 29-7-2005 at 06:39

Oh, you mean stramonium/jimsonweed/thornapple. IIRC, the anticholinergic properties of its alkaloids cause symptoms (sweating, tears, muscular effects) that may be construed to be signs of fear. ;)

The "beautiful lady" can also be expected to have similar effects...

sparky (~_~)

P.S. Well actually, it's hyoscyamine and scopolamine in Datura.

epck - 29-7-2005 at 15:35

Atropine as well. (Edit:atropine is dl-hyoscyamine, oops)

The tropane plants (Datura, Belladonna, etc) are deliriants rather than the more classsical psychedelics. Many people have horrific experiences on these plants but they do not directly cause a fear reaction. As Garage Chemist suggested go see the erowid stuff if you are interested.

I have never heard of a chemical which directly invokes the fear response. I would not be suprised if research on this has been done, since one could imagine a myriad of possible uses.

[Edited on 30-7-2005 by epck]

latentheat - 30-7-2005 at 17:55

Atropine is an effective antidote for organophosphate poisoning.

I just noticed the other day that al-chymist.com sells atropine sulfate (link).

Deliriants like the tropane alkaloids and diphenhydramine cause incredibly real delusions, not just alterations in the things you are seeing like LSD does. Scary stuff. Those that dabble in deliriants are brave. Atropine and some of the other tropane alkaloids are actually very toxic, messing with deadly nightshade/datura/mandrake root is risky business :o

I would say that they (deliriants) are fear inducing in a lot of situations.

[Edited on 31-7-2005 by latentheat]

sparkgap - 31-7-2005 at 17:03

"Atropine is an effective antidote for organophosphate poisoning."

Yes, that's why in wartime situations where nerve gases are expected to be used, you have to be carrying ampules of atropine and pralidoxime.

Isn't mandrake genus Podophyllum? That isn't a deliriant, it's more of an antimitotic used in treating verruca. Matter of fact, derivatives of the lignans present in mandrake are used as antineoplastics (e.g. etoposide and teniposide).

Besides, most of the anticholinergic alkaloids are in potato family (Solanaceae) plants, and mandrake isn't closely related to them.

(edit) After some Googling, however, I have found out that there are two, yes two, different plants called "mandrake". There is an "Atropa" mandrake and a "Podophyllum" mandrake (aka May apple). So I guess we're both correct. :D

sparky (~_~)

[Edited on 1-8-2005 by sparkgap]

latentheat - 31-7-2005 at 19:26

I'm pretty sure that mandrake is in the family solanaceae and the genus atropa just like deadly nightshade is.

Ok, I just checked wikipedia and erowid, and they both classify mandrake as being under the family solanaceae. Erowid gives the technical name of mandrake as atropa mandragora.

The_Simpsons - 16-6-2006 at 13:01

No im very sure it belongs to the genus Mandragora officially, before it was in Atropa. Btw organophopshates like VX, are they acetylcholinesterase-blockers? Atropine fits in perfectly as an antidote in that case.