Would it be better to order TCB from a supplier or to just chlorinate benzene myself?
Basically im looking for the more cost-effective method.gsd - 8-5-2006 at 09:21
which isomer?=SkyNET= - 8-5-2006 at 09:41
Right, 1,3,5.
Sorry bout that.
[Edited on 8-5-2006 by =SkyNET=]gsd - 8-5-2006 at 10:19
Chlorination of Benzene will result in cocktail of all sorts of CB compounds/isomers.
To the best of my knowledge 1,3,5 TCB is made by chlorinating Aniline - which gets symmetrically substituted to 2,4,6 Trichloroaniline and then
knocking off the -NH2 by diazo, yielding symmetrical 1,3,5 TCB.
[Edited on 8-5-2006 by gsd]=SkyNET= - 8-5-2006 at 17:34
Thanks.
Now just need to get some nitrobenzene.
I'd really rather not order anything from china right now
[Edited on 9-5-2006 by =SkyNET=]leu - 8-5-2006 at 18:00
Quote:
To the best of my knowledge 1,3,5 TCB is made by chlorinating Aniline - which gets symmetrically substituted to 2,4,6 Trichloroaniline and then
knocking off the -NH2 by diazo, yielding symmetrical 1,3,5 TCB.
That's correct, see JACS18 667 (1896) and Rec Trav Chim56 1177 (1937) for more details
Edit: Instead of JACS it should be Am Chem J18 667 (1896)
