Sciencemadness Discussion Board

Chloroform and Ammonia?

bigtrevs98 - 16-4-2015 at 16:25

"One big word of warning; DON't USE CHLorofrom with amines or NH3. They combine to create posions, isonitriles (AKA isocyanides, or carbylamines<--sp?)" Is this true? And if so can someone tell me the whole formula of the reaction and the names of the chemicals made





Anyone?

[Edited on 17-4-2015 by bigtrevs98]

Chemosynthesis - 16-4-2015 at 17:12

Where is this quote from? You should cite your source.
Did you search for this at all? You can still find information on it without knowing the name reaction through Google and not necessarily having to check any transformative reaction texts
(Hofman isonitrile synthesis).
http://en.wikipedia.org/wiki/Carbylamine_reaction
You can see the reactions are base catalyzed.

gdflp - 17-4-2015 at 09:55

Ammonia "will" react with chloroform to form cyanides, there are issues with the reaction though, see here http://www.sciencemadness.org/talk/viewthread.php?tid=23&...