Sciencemadness Discussion Board

MDA VIA PIPERONAL , USING I2 AND H3P03 TO REDUCE IT IS IT POSSIBLE?

Eskarari - 24-6-2015 at 11:37

Helllo i am wondering if anyone here could help me with a inquiry, can piperonal be reduced using I2 and h3p03 ( hypophosphorus acid) to convert it into MDA

As far as i can see is its similar to pseudoephidrine were it just requires an oxygen to be reduced of to convert to methamphetamine. .
Ive studied the molecular structure and i am almost convinced that a reduction using h3p03 and i2 would suffice, can i get some further information if possible please

Kind Regards. EsKaTaRi bLu♡

aga - 24-6-2015 at 11:47

We can't answer questions until you provide :-

your name, a photo, identity number, address (preferably GPS co-ordinates) of your cook-lab.

Provide those asap and we'll be with you very soon to 'help you out'.

Currently we wear black special ops uniforms for camoflage, and drive SWAT vans.

There's no need to let us in, we have a big heavy skeleton key that always works fine.

Eskarari - 24-6-2015 at 11:49

Lol cheeky

But seriously?

Eskarari - 24-6-2015 at 11:53

Do you want my doctoral degree information as well :p

Zephyr - 24-6-2015 at 11:55

If you have a doctorate you shouldn't need our help to figure this out...
Find a forum more accommodating of your branch or chemistry.

Eskarari - 24-6-2015 at 11:58

Any recommendations ? Im an organic chemist, i have performed various other synthesis routes
But my curiosity has led me to think about a much simpler i2/h3p03 reduction. .
I beleive it sounds plausible, simply looking for a second opinion. Before i waste heliotropin.



[Edited on 24-6-2015 by Eskarari]

turd - 24-6-2015 at 12:00

Quote: Originally posted by Eskarari  
Helllo i am wondering if anyone here could help me with a inquiry, can piperonal be reduced using I2 and h3p03 ( hypophosphorus acid) to convert it into MDA

No. You have to condense piperonal with nitroethane to a nitropropene and reduce that, for example with Al/Hg.

See: https://www.erowid.org/library/books_online/pihkal/pihkal100...

aga - 24-6-2015 at 12:07

This is an amateur science, mostly chemistry website.

Asking for Drug synths to further your Financial aims isn't any good for us at all, likey not for you either in the medium to long term.

Work it out for yourself Dr Eskarari and/or post helpful stuff to those asking questions NOT relating to illegal and desperately harmful drug synstheses.

With a Doctorate in OC you must be very well versed in chemistry, and be able to provide endless help and information.

I suspect you've gone already though.

Shame that the Only thing some chemists want is to harm people, make some money breifly, then spend a lot of time in prison, or dead.

[Edited on 24-6-2015 by aga]

Eskarari - 24-6-2015 at 12:08

I susepected as much with the nitrostyrene step.
My concern is with the polarity of piperonal being basically non polar.. a reduction with lithium alkali or sodium alkali and anhydrous NH4 would work as it is a freebase based reduction route.

It wouldn't work via a hypophosphorus and i2 reduction would it? As in my experience all starting constituents are always hydrochloride.
Or would it still reduce it all the same as the desired effect is occuring , that being a reduction of oxygen?

Eskarari - 24-6-2015 at 12:09

This is not for financial gain, I respect chemistry and the compounds to much to disrespect myself by doing that

I would never , have never, sold anything ive made.

Eskarari - 24-6-2015 at 12:12

I also hold a degree in neurological science and microbiology :)
Specialty in mycology :)

turd - 24-6-2015 at 12:15

Quote: Originally posted by Eskarari  
It wouldn't work via a hypophosphorus and i2 reduction would it?

No. I2/P is a very special reaction that transforms alcohols into alkanes. It is not a generally applicable reduction reaction.

Al/Hg is trivial and OTC.

The rest of your post is very confused. Try to formulate more clearly what you mean, perhaps with the help of a diagram.

Eskarari - 24-6-2015 at 12:19

Piperonal can be reduced into its alcohol form.

Eskarari - 24-6-2015 at 12:21

Hmmmm let me think

aga - 24-6-2015 at 12:21

Quote: Originally posted by Eskarari  
I also hold a degree in neurological science and microbiology :)
Specialty in mycology :)

I am a Monkey's Uncle.

[Edited on 24-6-2015 by aga]

Eskarari - 24-6-2015 at 12:25

Yeh well im your long lost monkey uncle ;)

Eskarari - 24-6-2015 at 12:27

Test me what do you wish to know in regards to aforementioned feilds

turd - 24-6-2015 at 12:36

Quote: Originally posted by Eskarari  
Piperonal can be reduced into its alcohol form.

And that (3,4-methylenedioxybenzyl alcohol) can probably (though with some pain) be reduced with P/I2 to the alkane (3,4-methylenedioxytoluene).
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302097/

Too bad that this cannot be turned into good ol' MDA (except perhaps by reoxidation to piperonal). Sorry.

Eskarari - 24-6-2015 at 12:45

:) thats a big 10 four

aga - 24-6-2015 at 12:50

Quote: Originally posted by Eskarari  
Test me what do you wish to know in regards to aforementioned feilds

Each of which would require at least a small degree of Spelling competence.

Seriously, expecting people to believe you have a Doctorate in OC, Mycolocy, Neurology, etc and asking about drug syntheses on a website like this ?

It's not even funny, just Sad.