bereal511 - 20-8-2015 at 19:07
I'm interested in synthesizing derivatives of l-cysteine ethyl ester and n-acetyl cysteine ethyl ester for in vitro trials of a hybrid (potential)
therapeutic. The aforementioned cysteine compounds appear to be better suited to crossing cellular membranes from a quick literature scan. That
being said, there's been little done on their potential toxicities in humans.
Ethyl esters of amino acids and other supplements have been known. For example, arginine ethyl ester is touted as a supplement for increasing NO in
muscle tissues with better bioavailability (although there's a lot of dispute over its increased efficacy over pure arginine).
Would anyone happen to have some insight? It's really a question of, why aren't there any cysteine ethyl esters being peddled on the market?