kamal - 17-8-2006 at 06:21
Hi to all...!!!!
I'm trying to get :
Ethyl-4-Bromo-3-Hydroxy butyrate from Ethyl-4-Bromo-3-Oxo-Butyrate.
I tried searching beilstein, orgsyn, etc. but not getting proper process for this. Only one with Sucrose & yeast as per orgsyn was there but is
very long & lazy process.....
May I get suggetions from you friends for this C=O to CH-OH reduction.....?
not_important - 17-8-2006 at 06:54
Try "Organic Reaction V2", the Meerwein-Ponndorf-Verley Reduction. There is a subsection on alpha-bromo-ketones.
Ref. papers
kamal - 19-8-2006 at 21:04
Do you have exact ref. journal paper suggetions for this ?
not_important - 19-8-2006 at 22:17
http://www.sciencemadness.org/library/index.html
Get Org Reactions V2, read the chapter; there's a slew of references although only a few for your specific case.
But if you must, or can't figure out how to download, try starting here:
http://people.bu.edu/jaylowe/Named%20reactions/M/MPV/meerwei...
R. M. Kellogg, Comp. Org. Syn. 8, 88-91 (1991)
C. F. de Graauw et al., Synthesis 10, 1007-1017 (1994).
Thanks!
kamal - 19-8-2006 at 23:02
Thanks dear !
I'm now collecting these ref. from our library......