labi - 27-10-2006 at 07:48
Brood is an extremely fast application for bioisostere prediction. Brood searches databases known chemical fragments at a rate of over 100 per second
to identify molecular fragments that are similar to a query fragment. Brood identifies bioisosteres by finding fragments with shape, chemistry and
electrostatics that are similar to a 3D query fragment.
about the application
http://www.eyesopen.com/products/applications/brood.html
appl and fix
http://rapidshare.de/files/22683458/Brood.v1.0-ACME.rar.html
http://rapidshare.de/files/22683810/Brood.v1.0-ACME.r00.html
best wishes