Sciencemadness Discussion Board

Grignard workup with water

quickgold123 - 20-1-2017 at 18:46

I know that you normally use a dilute acid solution to protonate the compound formed after the Grignard reaction to obtain the necessary alcohol, but I'm working with an alkenyl Grignard, and I'm worried that the acid may add to the double bond. Thus, I'm wondering if its feasible to just use water to protonate the compound, seeing that you'd need significantly higher temperatures to have water react with an alkene.

UC235 - 20-1-2017 at 18:57

an aq. solution of ammonium chloride is a typical workup when the product is acid sensitive.