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Author: Subject: How can I synthesise 2-methyl-4chlorophenol?
Shadeslayer
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mad.gif posted on 9-11-2018 at 04:13
How can I synthesise 2-methyl-4chlorophenol?


I need to synthesise MCPA. For that I have managed to synthesis Chloro acetic acid. I can't figure out exactly how to make 2-methyl-4chlorophenol. Can anyone help? Thank you! :)
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9-11-2018 at 06:17
Metacelsus
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[*] posted on 9-11-2018 at 10:46


You can try chlorinating 2-methylphenol (aka o-cresol). This will produce a mixture of the 4-chloro and 6-chloro products, which should be separable.

But why not just buy MCPA? It's widely available as an herbicide.




As below, so above.

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[*] posted on 10-11-2018 at 08:00


Quote: Originally posted by Shadeslayer  
I can't figure out exactly how to make 2-methyl-4chlorophenol.

using oxone - https://www.tandfonline.com/doi/full/10.1081/SCC-120002013

using bleach -http://nopr.niscair.res.in/bitstream/123456789/18605/1/IJCA%...
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