Protium
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Eugenol + HX --> sigh...
Has anybody found an effective and quantitative method of halogenating eugenol's terminal double bond?
thoughts:
1. bubbling HCl through cold ether solution.
2. Bubbling HCl through DMSO OR aqueous DMSO solution.
It just depends on how you look at it...
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Sandmeyer
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With HBr
J. Am. Chem. Soc.; 69; 1947; 1540.
65 percent yield; Indian J. Chem. Sect. B; 27; 1-12; 1988; 308-310.
There is also a Chem Rev paper on DMSO and it's use among other stuff to make ketones from alkenes, if memory serves me. Great paper, a lot of
fun chemistry can be done with DMSO. For instance benzaldehydes from benzylchlorides. Nice for chloromethylation freaks...
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Mush
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Quote: Originally posted by Sandmeyer  | J. Am. Chem. Soc.; 69; 1947; 1540.
65 percent yield; Indian J. Chem. Sect. B; 27; 1-12; 1988; 308-310.
There is also a Chem Rev paper on DMSO and it's use among other stuff to make ketones from alkenes, if memory serves me. Great paper, a lot of fun
chemistry can be done with DMSO. For instance benzaldehydes from benzylchlorides. Nice for chloromethylation freaks... |
Indian J. Chem. Sect. B; 27; 1-12; 1988; 308-310.
Syntheses of ( ± )-Deoxyschizandrin & the Lignan,
l,4-Bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane
A GUNASEKARAN & K BALASUBRAMANIAN*
Attachment: Indian J. Chem. Sect. B; 27; 1-12; 1988; 308-310..pdf (2.8MB)
This file has been downloaded 413 times
[Edited on 20-9-2017 by Mush]
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