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Author: Subject: Grignard workup with water
quickgold123
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[*] posted on 20-1-2017 at 18:46
Grignard workup with water


I know that you normally use a dilute acid solution to protonate the compound formed after the Grignard reaction to obtain the necessary alcohol, but I'm working with an alkenyl Grignard, and I'm worried that the acid may add to the double bond. Thus, I'm wondering if its feasible to just use water to protonate the compound, seeing that you'd need significantly higher temperatures to have water react with an alkene.
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UC235
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[*] posted on 20-1-2017 at 18:57


an aq. solution of ammonium chloride is a typical workup when the product is acid sensitive.
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