Sciencemadness Discussion Board
Not logged in [Login ]
Go To Bottom

Printable Version  
 Pages:  1  
Author: Subject: Leuckart reaction
Wolfram
Hazard to Others
***




Posts: 133
Registered: 13-10-2003
Member Is Offline

Mood: No Mood

[*] posted on 16-11-2003 at 10:29
Leuckart reaction


The leuckart reaction is used to produce amphetamine on huge scale in eastern Europe could someone write the reaction. What is actually happening?

[Edited on 7-9-2009 by Polverone]
View user's profile View All Posts By User
vulture
Forum Gatekeeper
********




Posts: 3331
Registered: 25-5-2002
Location: France
Member Is Offline

Mood: No Mood

[*] posted on 16-11-2003 at 11:04


20s of google searching:

http://themerckindex.cambridgesoft.com/TheMerckIndex/NameRea...

I'm getting fed up with that lazy attitude of yours.




One shouldn't accept or resort to the mutilation of science to appease the mentally impaired.
View user's profile View All Posts By User
Wolfram
Hazard to Others
***




Posts: 133
Registered: 13-10-2003
Member Is Offline

Mood: No Mood

[*] posted on 16-11-2003 at 11:09
OK thanx mr. Vulture


OK thanx mr. Vulture but could you tell me why ammuniumacetate doesn´t work?
View user's profile View All Posts By User
unionised
International Hazard
*****




Posts: 4078
Registered: 1-11-2003
Location: UK
Member Is Offline

Mood: No Mood

[*] posted on 16-11-2003 at 14:09


Because it's not a formate. That means it's not an aldehyde and so it's a lousy reducing agent. (didn't you spot the CO2 as a product?)
View user's profile View All Posts By User
vulture
Forum Gatekeeper
********




Posts: 3331
Registered: 25-5-2002
Location: France
Member Is Offline

Mood: No Mood

[*] posted on 16-11-2003 at 14:48


formate = salt of formic acid, methanoic acid.

That's not an aldehyde.

Formaldehyde is an aldehyde.




One shouldn't accept or resort to the mutilation of science to appease the mentally impaired.
View user's profile View All Posts By User
unionised
International Hazard
*****




Posts: 4078
Registered: 1-11-2003
Location: UK
Member Is Offline

Mood: No Mood

[*] posted on 16-11-2003 at 15:40


Thanks, but I knew that anyway.

X-CHO is an aldehyde.
HO-CHO is an aldehyde.
Formic acid is an aldehyde as well as an acid.

Formic acid gives a positive reaction with Tollen's reagent and Fehling's solution.
It's an unorthodox point of view, but it explains the fact that acetate dosn't work.
View user's profile View All Posts By User
vulture
Forum Gatekeeper
********




Posts: 3331
Registered: 25-5-2002
Location: France
Member Is Offline

Mood: No Mood

[*] posted on 17-11-2003 at 02:45


Aah I see what you're getting at. Indeed one could consider formic acid as an aldehyde too.



One shouldn't accept or resort to the mutilation of science to appease the mentally impaired.
View user's profile View All Posts By User
Wolfram
Hazard to Others
***




Posts: 133
Registered: 13-10-2003
Member Is Offline

Mood: No Mood

[*] posted on 19-11-2003 at 04:41


Sorry I ment if acetamide (not amoniumacetate) does work instead of ammoniumformate?
What is the usual way to P2P in eastern europe?
View user's profile View All Posts By User
narkar
Harmless
*




Posts: 4
Registered: 20-11-2003
Location: x
Member Is Offline

Mood: intrested

[*] posted on 20-11-2003 at 09:14


does aybody know the synt of this ketone. C6H5CH2COCH3:D
View user's profile View All Posts By User
acx01b
Hazard to Self
**




Posts: 59
Registered: 6-5-2004
Member Is Offline

Mood: No Mood

[*] posted on 6-5-2004 at 12:20


hey

I have a question i never founded the answer:

CH3-CO-CH2Cl + C6H5MgBr

the ketone reacts 1st ?
(to yield after hydrolysis 2-Phenyl 1-chloro Propan-2-ol)
or not ? :-)

and by the way 2-Phenyl 1-chloro Propan-2-ol would react on water too..

[Edited on 6-5-2004 by acx01b]
View user's profile View All Posts By User
Ephoton
National Hazard
****




Posts: 463
Registered: 21-7-2005
Member Is Offline

Mood: trying to figure out why I need a dark room retreat when I live in a forest of wattle.

[*] posted on 26-6-2008 at 02:45


kill this thread mine was nothing like this.
it brakes all the rules.
at least mine was or though with some mistakes with the ideas too LAH not against the
rules of the site.




e3500 console login: root
bash-2.05#

View user's profile View All Posts By User
brew
Hazard to Self
**




Posts: 96
Registered: 25-4-2008
Member Is Offline

Mood: enthralled

[*] posted on 26-6-2008 at 02:51


Just curious but what does BMK stand for.
View user's profile View All Posts By User
ScienceSquirrel
Super Moderator
*******




Posts: 1863
Registered: 18-6-2008
Location: Brittany
Member Is Offline

Mood: Dogs are pets but cats are little furry humans with four feet and self determination! :(

[*] posted on 26-6-2008 at 03:10


Quote:
Originally posted by brew
Just curious but what does BMK stand for.



Benzyl methyl ketone, another name for 1-Phenyl-2-propanone.
View user's profile View All Posts By User
Nicodem
Super Moderator
*******




Posts: 4229
Registered: 28-12-2004
Member Is Offline

Mood: No Mood

[*] posted on 30-6-2008 at 04:28


Quote:
Originally posted by Ephoton
kill this thread mine was nothing like this.
it brakes all the rules.
at least mine was or though with some mistakes with the ideas too LAH not against the
rules of the site.

Please discuss complaints about moderation either via U2U or in the Forum matters section. Besides, this thread is from 2003 and was resuscitated by Bluetooth without any solicitation or question on the topic, so your comparison to whatever action taken against any of your posts/threads is not really relevant. This thread does not break any forum rule. It is however not particularly informative, but for now that by itself is no reason to just "kill" it (though if it was a recent one it would go to Beginnings due to the laziness of the original poster in searching for any information on the topic prior to asking others to do so).
View user's profile View All Posts By User
Bluetooth
Harmless
*




Posts: 14
Registered: 19-8-2007
Member Is Offline

Mood: No Mood

[*] posted on 27-12-2008 at 02:00


There is a patent about the leuckart reaction that claims the leuckart reaction with a catalyst. They illustrate te amination of benzophenone with 6mol equivalent formamide and small amount MgCl2 at 170-190C under N2 atmosphere. After 4 hours and the product was isolated in a yield 95,6%.

The same experiment repeated with out catalyst under the same conditions gave a yield of only 21.7%.
:P
View user's profile View All Posts By User
Sauron
International Hazard
*****




Posts: 5351
Registered: 22-12-2006
Location: Barad-Dur, Mordor
Member Is Offline

Mood: metastable

[*] posted on 27-12-2008 at 05:00


Patent number, name of inventor, date, country? It's customary to cite these things.



Sic gorgeamus a los subjectatus nunc.
View user's profile View All Posts By User
JohnWW
International Hazard
*****




Posts: 2849
Registered: 27-7-2004
Location: New Zealand
Member Is Offline

Mood: No Mood

[*] posted on 27-12-2008 at 11:38


A search suggests that this is probably the patent Bluetooth means, but using boric acid or AlCl3, which were found to be superior, instead of MgCl2:

http://www.freepatentsonline.com/4851548.html (1989)
Here is a related one:
http://www.freepatentsonline.com/6596861.html

See also, besides erowid:
http://www.geocities.com/methamphetamine_x/
http://saevarr.com/drugs/Chrystalmeth/amphetamine.reduction....

The Leuckart reaction involving benzophenone and formamide, catalyzed by MgCl2, was described 40 years earlier. in Webers et al, JACS 70, 1422-4(1948) and Bunnett et al, JACS 71, 1587-9(1949). Someone with the necessary online access, please find and upload these articles.

[Edited on 28-12-08 by JohnWW]
View user's profile View All Posts By User
mr_burns
Harmless
*




Posts: 2
Registered: 27-12-2008
Member Is Offline

Mood: No Mood

[*] posted on 27-12-2008 at 22:27


The route to P2P using in eastern europe? Chemical companies, money, and guns. I read an interview with a DEA agent recently where he said that almost all E made in eastern europe was made from commercial MDP2P.

And if you actually wanted to make amphetamines, the leuckart is a ridiculously temperamental reaction to actually run. Wiki has a great overview of the reaction, just mentally substitute P2P in.
View user's profile View All Posts By User
sparkgap
International Hazard
*****




Posts: 1230
Registered: 16-1-2005
Location: not where you think
Member Is Offline

Mood: chaotropic

[*] posted on 27-12-2008 at 22:44


Quote:

The Leuckart reaction involving benzophenone and formamide, catalyzed by MgCl<sub>2</sub>, was described 40 years earlier. in Webers et al, JACS 70, 1422-4(1948) and Bunnett et al, JACS 71, 1587-9(1949).


:D

sparky (^_^)




"What's UTFSE? I keep hearing about it, but I can't be arsed to search for the answer..."
View user's profile View All Posts By User
Sauron
International Hazard
*****




Posts: 5351
Registered: 22-12-2006
Location: Barad-Dur, Mordor
Member Is Offline

Mood: metastable

[*] posted on 28-12-2008 at 01:35


My intention was not to solicit assistance for meth cooks. They can all go to hell. My intention was to prod bluetooth to post like a chemist, citing his sources rather than merely scattering bits of random information around in a long defunct thread.



Sic gorgeamus a los subjectatus nunc.
View user's profile View All Posts By User
kmno4
International Hazard
*****




Posts: 1365
Registered: 1-6-2005
Location: Silly, stupid country
Member Is Offline

Mood: No Mood

[*] posted on 29-12-2008 at 08:26


Quote:
Originally posted by mr_burns
The route to P2P using in eastern europe? Chemical companies, money, and guns.

Mostly from People's Republic of China :P
Another way is comonly known catalytic ketonisation - the simple
and cheap method.
A few days ago I saw pictures on TV from "laboratory" (just shed in the boonis) - all they showed was a fragment of pipe (tube) reactor and yellow something (yes, yes.... ) in a flask (placed in electrical heater) ready for Leucart (probably).
A few years ago, our police arrested men wanting to produce known ketone on almost industrial scale, hah. They have completed aparaturus but not yet running. Probably they wanted too much and unfair competition gave police a bell :P
Why Leuckart ?
Simple, cheap, clean, easily scaled up. My country is one of the famous producers of sulfate of known amine (mostly not methylated),from known ketone by this method.
I am not specially proud of it :)
Some lady told me that selling of ammonium formate was (is ?) strictly monitored, just because of Leuckart. But ammonia (or its carbonate) or formic acid are not specially controled. Stupid - isn't it ?

[Edited on 29-12-2008 by kmno4]
View user's profile View All Posts By User
Bluetooth
Harmless
*




Posts: 14
Registered: 19-8-2007
Member Is Offline

Mood: No Mood

[*] posted on 2-1-2009 at 15:11


Quote:
Origineel gepost door sparkgap
Quote:

The Leuckart reaction involving benzophenone and formamide, catalyzed by MgCl<sub>2</sub>, was described 40 years earlier. in Webers et al, JACS 70, 1422-4(1948) and Bunnett et al, JACS 71, 1587-9(1949).


:D

sparky (^_^)




[bewerken aan 2-1-2009 door Bluetooth]
View user's profile View All Posts By User
Bluetooth
Harmless
*




Posts: 14
Registered: 19-8-2007
Member Is Offline

Mood: No Mood

[*] posted on 2-1-2009 at 15:22


Quote:
Origineel gepost door mr_burns
The route to P2P using in eastern europe? Chemical companies, money, and guns. I read an interview with a DEA agent recently where he said that almost all E made in eastern europe was made from commercial MDP2P.

And if you actually wanted to make amphetamines, the leuckart is a ridiculously temperamental reaction to actually run. Wiki has a great overview of the reaction, just mentally substitute P2P in.


:D:cool:
Hey but i'm from the netherlands, or from HEERLEN AND my name isn't MAE BeeOK

[bewerken aan 2-1-2009 door Bluetooth]
View user's profile View All Posts By User
Bluetooth
Harmless
*




Posts: 14
Registered: 19-8-2007
Member Is Offline

Mood: No Mood

thumbup.gif posted on 14-1-2009 at 11:48


Here is the document i was talking about :
http://www.google.com/patents?id=k-BHAAAAEBAJ&printsec=d...
;)

[bewerken aan 14-1-2009 door Bluetooth]
View user's profile View All Posts By User
twodogs
Harmless
*




Posts: 10
Registered: 16-9-2006
Member Is Offline

Mood: No Mood

[*] posted on 14-1-2009 at 18:22


I wonder how this works. Notice it is non microwave!
http://www.articlearchives.com/science-technology/chemistry/...
View user's profile View All Posts By User
 Pages:  1  

  Go To Top