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Author: Subject: How is synthetic epinephrine prepared?
Douchermann
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[*] posted on 26-4-2009 at 00:10
How is synthetic epinephrine prepared?


Hey guys, I spent some time searching around, and all I could find was the biosynthesis, or people telling other people that they're stupid for asking. All for curiosities sake, I want to know how they make synthetic epinephrine. I, of course, wont be attempting to make any, as I have no use for it, but I just can't seem to find any literature or patents on it. The more I search, the more curious I become. Does anyone have any idea, or any literature on how they make this?



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Vogelzang
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[*] posted on 26-4-2009 at 08:29



http://books.google.com/books?id=n4I6AAAAMAAJ&pg=PA235&a...

http://books.google.com/books?id=MAA5AAAAIAAJ&pg=PA78&am...
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Douchermann
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[*] posted on 26-4-2009 at 09:22


Ah, okay, that makes sense. Well thank you very much



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[*] posted on 27-4-2009 at 04:38


Although I'm not one hundred percent sure, I belive epinephrine is synthesized by reaction between alpha-bromo(or chloro)-3,4-dihydroxyacetophenone and metylamine followed by reduction of the aminoketone to the amino alcohol.
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