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Author: Subject: Dextromethorphan
tom haggen
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[*] posted on 31-1-2004 at 21:54
Dextromethorphan


Does anyone no how to synthesize a opiate alkaloid from destromethorphan?



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Hermes_Trismegistus
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thumbdown.gif posted on 31-1-2004 at 23:10


That's an excellent question for a relevent forum like "the hive", or "lyceaum", or "Rhodium" etc....etc....etc.



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Blind Angel
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[*] posted on 1-2-2004 at 07:38


To quote Myself:
Quote:

You might like to take a look at this page which is pretty detailled .
BTW: Dextromethophan has no morphine/heroin/codeine... like activity (this is why it is disponible otc) and i don't think there's a way to turn it in something stronger (maybe playing with the R on the tertiary amine but i think that this work only on the Levotary isomer).


If you followed the link you'ld have seen that it pretty imposible to make it from Dextromethophan due to the piperidine ring being inverted in comparaison of the other opioid, also the ether link between the benzen and the cyclohexene would be pretty hard to reproduce.




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tom haggen
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[*] posted on 1-2-2004 at 12:02


Ya I looked at your link, it looked extremely difficult to try an use dextromethorphan.

[Edited on 1-2-2004 by tom haggen]




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