Metacelsus
International Hazard
Posts: 2531
Registered: 26-12-2012
Location: Boston, MA
Member Is Offline
Mood: Double, double, toil and trouble
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Methanesulfonyl azide as an antidote for hydrogen sulfide
Apparently methanesulfonyl azide is a decent H2S antidote (tested in mice). I'd have expected the azide to be toxic, but apparently the mice survive.
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.2019055...
Anyone up for some fun with azides?
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Sigmatropic
Hazard to Others
Posts: 307
Registered: 29-1-2017
Member Is Offline
Mood: No Mood
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I really, really, really hate supplementary information where the synthesis just reads: 'synthesized according to literature procedure'.
I mean sure, say that the procedures were adapted from literature and credit the original author, but by not describing the replication of the
procedure the work itself becomes less reproducible. Did it really go as described in literature, did they really obtain dry materials (if I must
believe the reported nnr spectrum) and how safe is that really?
I just do not feel like making contact explosives in a purity suitable for biological experiments with such meagerly discribed syntheses. So no
thanks, I will pass, I much enjoy having 10 digits.
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DavidJR
National Hazard
Posts: 908
Registered: 1-1-2018
Location: Scotland
Member Is Offline
Mood: Tired
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This is interesting but I agree that it seems unwise to attempt to synthesise this....
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