Toxicity of Aniline
Hi All,
I am considering an experiment that involves handling freebase aniline. I'm concerned about handling it because of its volatility and carcinogenic and
toxic properties. I've only ever handled its hydrochloride salt (produced by hydrolysis of acetanilide) to use in diazonations. Works pretty well, by
the way.
The process I'm doing involves heating it at 110C for 2 hours with paraformaldehyde and substituted phenols to make a derivative of benzoxazine. I'm
doing it on a 10 gram scale. Are there any other concerns here besides the obvious concern of formaldehyde vapors?
I have access to a respirator, goggles, gloves, lab coat, and a well-ventilated workspace. Do you think it's safe for me to handle freebase aniline
under these circumstances?
Thanks,
Jacob
Note: I posted this on Responsible Practices, but I'm also posting it here because maybe the people on this board will have a different take on it.
Sorry if this isn't good practice, I'm new here.
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