bluamine
Hazard to Others
Posts: 196
Registered: 17-8-2015
Member Is Offline
Mood: No Mood
|
|
how to make methylbenzylamine ??
Hi everyone!!
Guys, does anyone know a process to synthesize methylbenzylamine from any benzene derivatives, please?
[Edited on 22-6-2022 by bluamine]
|
|
|
Corrosive Joeseph
National Hazard
Posts: 915
Registered: 17-5-2015
Location: The Other Place
Member Is Offline
Mood: Cyclic
|
|
Zn-Ni-NH3 reductive amination of acetophenone
/CJ
Being well adjusted to a sick society is no measure of one's mental health
|
|
|
bluamine
Hazard to Others
Posts: 196
Registered: 17-8-2015
Member Is Offline
Mood: No Mood
|
|
Does it require only elemental Zn/Ni or complexes containing them instead?
I read on Wikipedia that must be don under high pressure (238-340 ATM!!)
[Edited on 22-6-2022 by bluamine]
|
|
|
Texium
Administrator
Posts: 4508
Registered: 11-1-2014
Location: Salt Lake City
Member Is Offline
Mood: PhD candidate!
|
|
CJ describes making 1-phenylethylamine. Is that what you want, or are you trying to make N-methylbenzylamine? That can be done by reductive amination
of benzaldehyde with methylamine and sodium borohydride.
|
|
|
bluamine
Hazard to Others
Posts: 196
Registered: 17-8-2015
Member Is Offline
Mood: No Mood
|
|
Quote: Originally posted by Texium  | | CJ describes making 1-phenylethylamine. Is that what you want, or are you trying to make N-methylbenzylamine? That can be done by reductive amination
of benzaldehyde with methylamine and sodium borohydride. |
Both are interesting but anyway, I'm more interested in N methylbenzylamine
|
|
|
karlos³
International Hazard
Posts: 1520
Registered: 10-1-2011
Location: yes!
Member Is Offline
Mood: oxazolidinic 8)
|
|
Reductive amination of benzaldehyde with methylamine then.
Straight forward and simple, high yielding likely too.
verrückt und wissenschaftlich
|
|
|
Texium
|
Thread Moved
22-6-2022 at 10:44 |
![[*]](images/xpblue/default_icon.gif){kind=icon}
