PainKilla
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Caffeine
Caffeine seems like a pretty cool substance being that it is legal and has similair properties to many illegal substances...though of course I do not
want to manufacture any of these these substances, it would definetly be an awesome way to waste some time.
From what I understand caffiene (1,3,7-trimethylxanthine) or C8H10N4O2, affects the adenosine receptors by binding to them inplace of adenosine. This
causes the body to panic essentially releasing adrenaline and small amounts of dopamine. This of course, giving you the relaxed yet alert feeling.
Since caffeine is such an easy substance to obtain/extract, I am curious if there is any intersting compounds that can be synthesized off of it.
Preferably NOT illegal substances. Makes me wonder of what more powerful undiscovered anologues do...
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kyanite
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I think Erowid's vaults have something about this... like analogues or something, where the methyl groups are different.
By the way, caffeine is part of a family called Xanthines. Hope that helps.
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unionised
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I gather that recent work has shown that theobromine, another methylated xanthine, is good at suppressing the cough reflex. (better than codiene)
Bizzarrely, this means that chocolate is good for you.
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Titan
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Caffeine,
a bitter substance ?
[low-effect-drug]
Adenosines are a ingredient of the DNA structures. (bases-pairs) ?
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sparkgap
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Yes, it's bitter. Most alkaloids, and in fact, most bases, tend to be bitter-tasting.
Yes, adenosine is a DNA building block.
Yes, your English syntax is freakishly weird. The needle of my troll-detector is kicking a bit...
sparky (^_^)
"What's UTFSE? I keep hearing about it, but I can't be arsed to search for the answer..."
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joe_aldehyde
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as far as i know, all the xanthines have some pharmacological importance, such as theophylline, theobromine, caffeine, and so on. i have recently made
some dervatives of uracil which is a precursor to the xanthines, but i don't know of any xanthines that have the attributes you are looking for.
stick to your guarana powder 
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Mr. Wizard
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Would that be your bot troll detector? I see what you mean.
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kyanite
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Maybe its the_gender_changer!
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neutrino
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I doubt it. Too much coherency, not enough emoticons.
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Titan
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sparkgap,
i had looked up for the DNA biochemicals.
Adenosine base-pair  block chemical  .
Adenin and cytosin DNA or RNA Chemicals.
I`m no a biochemist.
Caffeine - bitter substance (concentreted tasteless) .
teeine - bitter substance (concentreted tasteless) .
But whats is the caseine ?
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sparkgap
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Titan:
Quote:
Caffeine - bitter substance (concentreted tasteless) .
teeine - bitter substance (concentreted tasteless) .
Eh? What do you wish to speak about now?
Clarify, please. Methinks, however, that the more there is of something, the more potent the taste.
Casein is one of the proteins that comprise milk. It is in no way related to caffeine.
neutrino, he is now using emoticons. My troll-detector needle is still wagging. What do you think?
sparky (^_^)
P.S. If guarana don't work for you, kava might be, shall I say, "your cup of tea".
"What's UTFSE? I keep hearing about it, but I can't be arsed to search for the answer..."
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cyclonite4
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I'll say he is quite more literate, but still a TGC style idiot. Damn his/her dynamic IP.
I say it's TGC enough...
\"It is dangerous to be right, when your government is wrong.\" - Voltaire
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sparkgap
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We must admit, however, that TGC set the gold standard for incoherence and inanity here at MSDB.
sparky (^_^)
"What's UTFSE? I keep hearing about it, but I can't be arsed to search for the answer..."
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cyclonite4
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He practically set a new acronym for stupidity, and various gentic disorders. That acronym is... well, you know. 
[Edited on 1-4-2005 by cyclonite4]
\"It is dangerous to be right, when your government is wrong.\" - Voltaire
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neutrino
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I don't know, it's still only two <i>different</i> emoticons. I'd definitely call it a possibility, though.
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akinmad
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I've been here for a long time but this is my second post, I believe.
(My previous post was related to synthesis of creatine).
I have read somewhere Caffeine was hydrolized to sarcosine (an aminoacid) which is a precursor of Creatine synthesis. As you may know the creatine
stuff is used for enhancing muscle performance and tonus. Actually it's naturally present in muscle tissues and consumed during muscle activity.
HTH.
Edit : My post count shows 9. How can it be? I thought I only posted twice in past
[Edited on 2-4-2005 by akinmad]
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12AX7
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| Quote: | Originally posted by akinmad
Edit : My post count shows 9. How can it be? I thought I only posted twice in past
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Guess not, the FIND button on your post shows the threads...
http://67.15.145.24/~sciencem/talk/misc.php?action=search&srchuname=akinmad&searchsubmit=a&srchfid=all&srchfrom=0
Tim
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sparkgap
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Any references for that, akinmad? I don't see how caffeine can be hydrolyzed into sarcosine.
sparky (^_^)
"What's UTFSE? I keep hearing about it, but I can't be arsed to search for the answer..."
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akinmad
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IIRC it is hydrolyzed into Sarcosine by means of Barium
Hydroxide (a nasty compound). However I cannot find any reference for the time being although it is present in my PGP disks. However I found reference
for the purin here it is. Whenever I have time I shall attach the file here. But I have more than 10 GB content placed in PGP disks, which makes it cumbersome
to find a specific file. (In addition it is 4:30 am in the morning here)
In addition this link which I have difficulty opening it, has some reference that caffeine is synthetically made from sarcosine and cyanamid.
Another link which is actually a PDF file. My bad. The text says caffeine thermally decomposed into sarcosine in presence of barium carbonate not barium
hydroxide. Please check page 18.
This patent also mentions about thermal decomposition of Caffeine into sarcosine but in presence of Barium hydroxide. HTH.
Weird but I cannot find this patent on US patent office
[Edited on 4-4-2005 by akinmad]
[Edited on 4-4-2005 by akinmad]
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sparkgap
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The reason I was asking was because I haven't encountered hydrolysis reactions for caffeine, but I do seem to recall the thermal decomposition as
part of research done in the past. Sorry and thanks.
sparky (^_^)
"What's UTFSE? I keep hearing about it, but I can't be arsed to search for the answer..."
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