Sciencemadness Discussion Board
Not logged in [Login ]
Go To Bottom

Printable Version  
Author: Subject: Friedel-crafts acylation temperature question
Bonee
Harmless
*




Posts: 26
Registered: 20-12-2010
Member Is Offline

Mood: No Mood

[*] posted on 3-3-2014 at 00:22
Friedel-crafts acylation temperature question


Is there any rationale lowering the temperature of a FC acylation to -70?
and doing it in a dry ice/acetone bath?
most preps are doing it at 0, but then other people use -70...
I couldn't find anything about it on the net or in books...
View user's profile View All Posts By User
Chemosynthesis
International Hazard
*****




Posts: 1071
Registered: 26-9-2013
Member Is Offline

Mood: No Mood

[*] posted on 3-3-2014 at 00:30


Is there a noticeable difference in reaction scale between the two temperatures?
View user's profile View All Posts By User
Bonee
Harmless
*




Posts: 26
Registered: 20-12-2010
Member Is Offline

Mood: No Mood

[*] posted on 3-3-2014 at 03:09


no, not really, that's why i am curious
true that it may be easier to control a bigger batch with lower temperatures.
but is there any literature involving increased yield, or anything else?
View user's profile View All Posts By User
Nicodem
Super Moderator
Thread Moved
3-3-2014 at 13:22

  Go To Top