Sciencemadness Discussion Board
Not logged in [Login ]
Go To Bottom

Printable Version  
Author: Subject: Easy synth. of hypno/sedative substances?
kazaa81
Hazard to Others
***




Posts: 368
Registered: 30-4-2004
Member Is Offline

Mood: ok

thumbup.gif posted on 5-2-2005 at 13:56
Easy synth. of hypno/sedative substances?


Hallo to all,
I'm searching for easy (possibly home) synthesis of "hypno" (in a medicine's manual I've find writed like that) and/or "sedative" substances...chloroform is a good know synthesis, so don't discuss this here.

Thanks at all for help
View user's profile View All Posts By User
The_Davster
A pnictogen
*******




Posts: 2861
Registered: 18-11-2003
Member Is Offline

Mood: .

[*] posted on 5-2-2005 at 15:44


Well, there is chloral hydrate whch is used in commercial sleep medicine, chlorobutanol which is quite similar to chloral hydrate, and there is also GBL/GHB.

This could have been easily found by searching and even your title of this thread is incorrect, there is a major difference between hypno substancs and sedatives.


[Edited on 5-2-2005 by rogue chemist]




View user's profile View All Posts By User
Geomancer
Hazard to Others
***




Posts: 228
Registered: 21-12-2003
Member Is Offline

Mood: No Mood

[*] posted on 5-2-2005 at 19:07


Check out the Rhodium mirror du jour. The suggestions you already have cover all I can think of that are really easy to make, except, of course, for ethyl alcohol. Benzodiazapines set the standard, but are much harder to make. I think that chloroform, diethyl ether (you can make this too), etc. form a completly different class of drugs.
View user's profile View All Posts By User
Sandmeyer
National Hazard
****




Posts: 784
Registered: 9-1-2005
Location: Internet
Member Is Offline

Mood: abbastanza bene

[*] posted on 8-2-2005 at 04:08


polymerization of acetaldehyde leads to a compound with hypnotic properties. You can make acetaldehyde by boiling ethanol and allowing the vapour to pass over a copper-wire, there are details on the internet.



View user's profile View All Posts By User
Esplosivo
Hazard to Others
***




Posts: 491
Registered: 7-2-2004
Location: Mediterranean
Member Is Offline

Mood: Quantized

[*] posted on 8-2-2005 at 04:35


IIRC the tetramer (which is solid) is said to have hypnotic properties. It was known as metaldehyde and it is produced by treating small amounts of acetaldehyde with acids such as HCl or sulfur dioxide. It was used as a solid fuel and as a toxic garden bait for slugs and snails.

The trimer is easily produced by adding a small quantity of conc. sulfuric acid to ethanal (acetaldehyde). The liquid mixture boils up suddenly. On addition of water a little pale yellow oil is seen to separate. This is the trimer, paraldehyde.

Sandmeyer, or anybody, could you please verify which one of the two polymers is the one with hypnotic properties? I think it was the tetramer but I am not sure.




Theory guides, experiment decides.
View user's profile Visit user's homepage View All Posts By User
Sandmeyer
National Hazard
****




Posts: 784
Registered: 9-1-2005
Location: Internet
Member Is Offline

Mood: abbastanza bene

[*] posted on 8-2-2005 at 05:09


Quote:
Originally posted by Esplosivo
Sandmeyer, or anybody, could you please verify which one of the two polymers is the one with hypnotic properties?


The one you obtain when you put one drop of conc H2SO4 per 2 mL of acetaldehyde... Formula: C6H12O3




View user's profile View All Posts By User
chemoleo
Biochemicus Energeticus
*****




Posts: 3005
Registered: 23-7-2003
Location: England Germany
Member Is Offline

Mood: crystalline

[*] posted on 8-2-2005 at 05:52


It's paraldehyde that has hypnotic properties (in case that wasn't clear from the above).
Does anyone know its side effects? Does depolymerisation occur in the body, during degradation? Surely that can't be too healthy?
But then, this probably depends of the dosis needed, I remember the sweetener aspartame that liberates methanol upon digestion, it turns out the amounts are minor compared to those taken up with a couple of glasses of beer.




Never Stop to Begin, and Never Begin to Stop...
Tolerance is good. But not with the intolerant! (Wilhelm Busch)
View user's profile View All Posts By User
vulture
Forum Gatekeeper
*****




Posts: 3330
Registered: 25-5-2002
Location: France
Member Is Offline

Mood: No Mood

[*] posted on 8-2-2005 at 11:40


*COUGH*

Is it just me or is this forum turning into a hive replacement?




One shouldn't accept or resort to the mutilation of science to appease the mentally impaired.
View user's profile View All Posts By User
Organikum
resurrected
*****




Posts: 2329
Registered: 12-10-2002
Location: Europe
Member Is Offline

Mood: busy and in love

[*] posted on 8-2-2005 at 12:14


Its just you.

Take your valium and calm down.

/ORG




Irgendwas is ja immer
View user's profile View All Posts By User
The_Davster
A pnictogen
*******




Posts: 2861
Registered: 18-11-2003
Member Is Offline

Mood: .

[*] posted on 8-2-2005 at 15:46


I agree with Vulture on this...



View user's profile View All Posts By User
Darkfire
Hazard to Others
***




Posts: 292
Registered: 3-1-2003
Location: California
Member Is Offline

Mood: Wondering

[*] posted on 8-2-2005 at 15:55


These kind of threads make this forum look like a cheap hive replacement; however, threads like cycloknights benzaldahyde thread do the oposite. There are alot more mind altering discusions on MSDB latley but if presented right they are fine.



\"I love being alive and will be the best man I possibly can. I will take love wherever I find it and offer it to everyone who will take it. I will seek knowledge from those wiser and teach those who wish to learn from me.\" Duane Allman
View user's profile View All Posts By User

  Go To Top