Sriraman
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Registered: 24-3-2006
Location: India
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4-methylpropiophenone
When we convert toluene to 4-methylpropiophenone using propionyl chloride by Friedel Craft's reaction, we get up to 10% 2-methylpropiophenone. How can
this be avoided, where by I get only 4-methylpropiophenone.
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runlabrun
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Registered: 4-12-2004
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alternative isomers yielded from this is always an occurence, it cannot be avoided unless you protect the 2 position, anyway a 90% correct isomer
yeild aint that bad... why worry?
-rlr
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