RareEarth
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Acylation of alcohol with acyl chloride - effect on chirality?
I was having a little difficulty finding information on this. If an acyl chloride is reacted with a chiral alcohol, is the chirality inverted, or
retained? I couldn't find any information whether this would be an SN1 or an SN2, but maybe I didn't look in the right place yet.
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Etaoin Shrdlu
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It's neither SN1 nor SN2.
Look at the reaction closely. On which atom are you worrying about chirality?
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blogfast25
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http://www.chemguide.co.uk/mechanisms/addelim/alcohol.html#t...
Can't see how chirality can be affected here.
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RareEarth
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Ah, you guys are right. I had a brain fart moment there. My brain seemed to be mixing up information about alkyl halide/alcohol reactions and acyl
chlorides.
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