Sciencemadness Discussion Board
Not logged in [Login - Register]
Go To Bottom

Printable Version  
Author: Subject: The PhenylEthylAmine from Vanillin
BezeneBoy
Harmless
*




Posts: 3
Registered: 27-11-2017
Member Is Offline

Mood: No Mood

[*] posted on 27-11-2017 at 13:42
The PhenylEthylAmine from Vanillin



A lot of the current Amphetamines and PhenylEthylAmines described to be active psychedelics from works like PIKHAL, use the right substituted benzaldehyde as starting material.
Benzaldehyde itself is banned, but one of the most common aromatic aldehydes we have is Vanillin. The molecule poses a 4 hydroxy group and 3 methoxy group, hence some potential as a stimulant can be expected if its linked in the Amphetamine Backbone.
Sadly Shulgin didn't explore this compound because it contains a hydroxy group on the ring, something that doesn't occour in his book, maybe because they are inactive, but there is no mention to that.
Nevertheless, it would be amazingly simple to prepare;
Just the classic NitroEthane -> then reduction method
or NitroMethane -> Reduction (to the Phenyl Ethyl Amine )

Additionally, using Methyl Iodide with NaOH under reflux in DCM with the Vanelin would yield the Di-Methoxy Aldehyde which yields 3,4-DMA by our previos scheme, but the sad part is, Shulgin didn't extensively study this compound himself, but it is mentioned to have activity.

This Di Methoxy however can be converted to piperional, which is a precursor a drug that I won't mention;

It is a compound that is so easily made, but yet no one seems to be interested in it, I haven't heard clandestine chemist making 3,4-DMA or using Vanillin to make this other drug. This isn't encouragement to do so, but any idea's why this isn't being done ?
View user's profile View All Posts By User
Bert
Super Administrator
*********




Posts: 2705
Registered: 12-3-2004
Member Is Offline

Mood: " I think we are all going to die. I think that love is an illusion. We are flawed, my darling".

[*] posted on 27-11-2017 at 15:22




Read the FAQ.

Board Topics- Mad Science FAQ


Quote:

It is okay to be ignorant when first arriving and posting. However, you must be willing to make an effort to learn. If you are unable to cite references in support of an idea or as background to your question, the post belongs in Beginnings. Questions that provide background information and show effort are more likely to receive good responses.

If an existing thread covers the topic you're about to post about, post in that thread instead of a new one. It makes it easier for members to keep up with topics of interest. You may need to search before posting if you're unsure whether or not a thread already exists. The search engine is not very powerful and may miss relevant threads, but please make at least a cursory effort.

Do not request spoonfeeding of information for clandestine drug manufacture. However, every sort of chemistry is a permissible topic of discussion if you discuss it like a scientist. If someone is asking about obtaining chemicals used in drug manufacture and using the vocabulary of a SWIM—"someone who isn't me"—-mer more than a chemist, report it and the thread will be dealt with after a moderator has confirmed your findings. Similarly, if someone is asking for help with a synthetic "recipe" for a known street drug, report that too. Don't bother to berate the cooks in the thread itself instead; that doesn't bring the mods any faster. In truth the mods and most members dislike any thread where someone is seeking or using a "recipe" and doesn't show any deeper interest in chemistry, but this has been mostly a problem with drug synthesis because of the many people who want to quickly get rich or high.

Certain topics are unwelcome no matter what section they are posted in. The discussion of criminal enterprises or weapons production is inappropriate.




Rapopart’s Rules for critical commentary:

1. Attempt to re-express your target’s position so clearly, vividly and fairly that your target says: “Thanks, I wish I’d thought of putting it that way.”
2. List any points of agreement (especially if they are not matters of general or widespread agreement).
3. Mention anything you have learned from your target.
4. Only then are you permitted to say so much as a word of rebuttal or criticism.

Anatol Rapoport was a Russian-born American mathematical psychologist (1911-2007).

View user's profile View All Posts By User
Bert
Super Administrator
Thread Moved
27-11-2017 at 15:23

  Go To Top