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Author: Subject: The neurochemicals in nature
symboom
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[*] posted on 4-1-2021 at 23:04
Kanna extract analysis


Here is a report I got with my kanna extract

IMG_20210105_005525039~2.jpg - 1.3MB IMG_20210105_010027713_BURST000_COVER_TOP~2.jpg - 1.1MB

Here is an NMR of matrine and general information about the extract


IMG_20210105_011502016~2.jpg - 1.3MB IMG_20210105_011450520~2.jpg - 1.1MB

[Edited on 5-1-2021 by symboom]
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scienceboi
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[*] posted on 5-1-2021 at 09:15


I really enjoy this thread. SM mostly stays away from "pharma type" chemicals and there's good reason for that. However, your effort of cataloging the various neurochemicals that plants and fungi naturally make is appreciated.

My favorite of your list so far is Hodgkinsine. I'd take a guess that it would replace kratom if kratom is fully illegal and scheduled.




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symboom
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[*] posted on 5-1-2021 at 09:48



Thank you that's great to hear.
akuamma is normally used as the replacement of kratom In places where it is illegal it is very similar herb that is from Africa unlike Kratom which is from Asia. They are very similar in that they are both partial opioids.
I put a lot of effort in this thread I was frustrated that there is so little research being done on these plants due to synthetic equivalent compounds already existing but now researches are discovering that there are better and safer alternatives from nature
So little information is found about many of the herbs I think it has to do with cost if a pharma company need to make a compound it is made syntheticly rather than extracted
Here is the research on kratom compounds and why a future synthetic partial opioid based on the structure kratom is being considered.
(Synthetic because a plant can't be patented)
https://pubs.acs.org/doi/10.1021/jacs.6b00360

MGM-9 kratom synthetic analog
https://www.sciencedirect.com/science/article/abs/pii/S00283...
And other MGM compounds
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067406/


Hodgkinsine is unfortunately hard to find a lot of information about.

[Edited on 5-1-2021 by symboom]

[Edited on 6-1-2021 by symboom]
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karlos┬│
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[*] posted on 5-1-2021 at 12:39


I have almost two kilos of akuamma(I even got a fresh fruit directly from a German farmer in Ghana but sadly the seeds haven't germinated without going through an elephants digestive system) but I have to say, its not a replacement for kratom.
It is pretty good against pain and cold and the flu, and thats really where its strength is, but it is not an euphoric opioid in the same manner as kratom.
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