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Author: Subject: Acetylation of sulphate salts
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[*] posted on 8-11-2007 at 02:16
Acetylation of sulphate salts


Acetylation with acetic anhydride ive always seen take place on freebase compounds.

And no one has been able to tell me otherwise... but ive got a USP pharmaceuticul grade compound that is usually acetylated as its freebase. However since its in its pure state but has a sulphate attached to it, can that be used directly in an acetylation?
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organometallic
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[*] posted on 8-11-2007 at 12:51


Why not convert to the freebase form? This is done I believe with ammonia; If i'm wrong please correct me with a minimum of flaming :p
PS, you may have better luck asking at www.wetdreams.ws




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[*] posted on 8-11-2007 at 15:12


well that is certainly possible, i was just wondering if it was possible. It would save alot of hassle because the acetylation requires anhydrous conditions so im trying to avoid using water at all.
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[*] posted on 8-11-2007 at 17:44


Is this a di-acetylation by any chance?



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[*] posted on 8-11-2007 at 18:02


yes, but not of any illegal compounds.
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[*] posted on 8-11-2007 at 22:39


a diactylation of a pharmaceutical sulfate that is not an illegal compound? I guess not if you have a prescription. Around here those are three pages. ahem! Also, if you can't liberate a freebase you better stay away from acetylations. The one you're thinking of is notorious for fires and explosions.

anyway, go here: www.wetdreams.ws

[Edited on 8-11-2007 by chemrox]




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[*] posted on 9-11-2007 at 15:25


Unless you name the actual compound, I'm gonna close this for being a drug thread.



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[*] posted on 9-11-2007 at 17:27


acetyl salicylicacid
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[*] posted on 9-11-2007 at 17:45


lol, since when is aspirin a sulfate salt
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[*] posted on 9-11-2007 at 17:52


haha well i guess its all just hypothetical then...
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[*] posted on 10-11-2007 at 03:57


Haha. Thread closed.

Take your cooking bussiness elsewhere.




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