Sciencemadness Discussion Board
Not logged in [Login - Register]
Go To Bottom

Printable Version  
 Pages:  1  2
Author: Subject: Phenylpropanones (P2P) from anilines
Dorsoris
Unregistered




Posts: N/A
Registered: N/A
Member Is Offline


[*] posted on 16-6-2018 at 16:08
Acetone to P2P via ketene


I'm working on a scheme involving an upgrading of acetone involving pyrolysis to form intermediate ketene which is further reacted with acetone to formisopropenyl acetate which is separated from the reaction as a liquid.

The isopropenyl acetate is reacted further with diazotized aniline to form phenyl-2-propanone(P2P). I can delete & repost this part if this is not the correct forum for P2P chemistry.

[file]68881[/file]

P2P from acetone via ketene.jpg - 25kB
Dorsoris
Unregistered




Posts: N/A
Registered: N/A
Member Is Offline


[*] posted on 16-6-2018 at 16:20


This chemistry was developed by a major chemical company around the m-trifluoromethyl derivative as a starting material for the now banned diet drug fenfluramine. It's still in a box of my file cabinet contents from a move.
Dorsoris
Unregistered




Posts: N/A
Registered: N/A
Member Is Offline


[*] posted on 16-6-2018 at 18:14


I envision 2 zones: first, the high temperature reaction zone to convert acetone feed into ketene in the vapor phase; second, a reaction zone where the ketene would be reacted with an excess of acetone followed by a condenser phase where the mixed acetone & isopropenyl acetate would be isolated as a mixture of 2 liquids. This mixture would be fractionally distilled to remove the more volatile acetone, which would be recycled.
zed
International Hazard
*****




Posts: 1647
Registered: 6-9-2008
Location: Great State of Jefferson, City of Portland
Member Is Offline

Mood: Semi-repentant Sith Lord

[*] posted on 25-6-2018 at 16:09


There is a YouTube video on the subject.

https://www.youtube.com/watch?v=g9sPlMkYEIw&t=188s

Excellent opportunities for death, while working with Ketene.

Likewise, Anilines and Benzene Diazonium Salts.

[Edited on 26-6-2018 by zed]

[Edited on 26-6-2018 by zed]
View user's profile View All Posts By User
VSEPR_VOID
National Hazard
****




Posts: 498
Registered: 1-9-2017
Member Is Offline

Mood: napalm in the morning

[*] posted on 26-6-2018 at 19:41


I am working on something a lot better, starting maybe from either aspirin, beznyl alcohol, or benzoic acid; not anilines.



Selling large quantities of sodium metal for cheap
https://www.etsy.com/listing/619459301/sodium-metal-100g?ref...

Of all the so-called natural human rights that have ever been invented, liberty is least likely to be cheap and is never free of cost
View user's profile View All Posts By User
 Pages:  1  2

  Go To Top