Sciencemadness Discussion Board

How is synthetic epinephrine prepared?

Douchermann - 26-4-2009 at 00:10

Hey guys, I spent some time searching around, and all I could find was the biosynthesis, or people telling other people that they're stupid for asking. All for curiosities sake, I want to know how they make synthetic epinephrine. I, of course, wont be attempting to make any, as I have no use for it, but I just can't seem to find any literature or patents on it. The more I search, the more curious I become. Does anyone have any idea, or any literature on how they make this?

Vogelzang - 26-4-2009 at 08:29

Douchermann - 26-4-2009 at 09:22

Ah, okay, that makes sense. Well thank you very much

Barium - 27-4-2009 at 04:38

Although I'm not one hundred percent sure, I belive epinephrine is synthesized by reaction between alpha-bromo(or chloro)-3,4-dihydroxyacetophenone and metylamine followed by reduction of the aminoketone to the amino alcohol.