fusso - 9-5-2019 at 03:57
I cant see the relationship between a substance's properties and whether it can enter body through skin. HF, Me2Hg, DMSO, Me2SO4 are examples that
can, but they have wildly different properties, and wiki didnt mention whether H2O can or not. So what make a substance able to enter body through
skin?
kulep - 9-5-2019 at 05:19
Your skin is covered in sebum, sebum helps lubricate and waterproof it. According to wikipedia:
Sebum, secreted by the sebaceous gland in humans, is primarily composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free
fatty acids (≈16%)
You can chemically remove it, that's why your hands feel dry after washing dishes or using alcohol hand sanitizer. It greatly increases skin
permeability.
You have to keep in mind that the skin isn't really very thick. Although epithelial cell's junctions are very tight any substance that could penetrate
the cell membrane (phospholipids) could enter, that's most organic solvents, even taking into account that live cells in the upper layers of the
epidermis are completely full of proteins.
https://en.wikipedia.org/wiki/Human_skin#Increasing_permeabi... here's some info
https://en.wikipedia.org/wiki/Sebaceous_gland#Sebum
Morgan - 9-5-2019 at 07:26
Something that penetrates
https://www.livescience.com/65416-sunscreen-chemicals-blood....