Sciencemadness Discussion Board

Lithium orotate

Nemo_Tenetur - 12-3-2026 at 01:32

Hi!

Lithium orotate triggered my interest because I´m suffering problems with my short-time memory. A quick internet-search revealed that this could be an early sign of a beginning Alzheimer´s desease ( I´m 50 + years old).

Even if my problems are more likely related to ADHD, I´m still interested in this topic.

There are several recent publications about the possible benefits of low-dosage Lithium orotate supplementation:

https://www.nature.com/articles/s41586-025-09335-x

In German language:

https://www.esanum.de/fachbereichsseite-neurologie-psychiatr...


Please do not confuse this with the high-dosage Lithium carbonate treatment of bipolar disorders!

In the U.S. and Canada, Lithium orotate is available as food supplement and sold OTC. In the EU, however, it´s not allowed as a food supplement ingredient and here in Germany, it´s even classified as "prescription only".

I don´t want to order it online from a seller outside the EU as this could lead to serious trouble with customs office. So I want to prepare it myself, solely for personal use/consumption without the intent of distribution, that´s legal.

The precursor Orotic acid is available as anhydrous acid and as the monohydrate. Lithium orotate exist also as anhydrous salt and as the monohydrate, but I was unable to find detailed information (melting point , solubility etc.).

I guess that the preparation of Lithium orotate in aqueous solution (Lithium carbonate and Orotic acid) always yield the monohydrate. Probably the monohydrate is stable at room temperature, but I have no idea about the stability against elevated temperature.

The precipitated Lithium orotate is a thick thixotropic gel, much like curd cheese and really a pain in the ass to work with. It will take a very long time to dry this mess, If possible at all within a reasonable time.

So I would like to know until which temperature the monohydrate is stable. I don´t want to get a partially dehydrated mixture of the monohydrate and the anhydrous salt as this complicates the exact dosage.

Comments and additional information about this topic is greatly appreciated.



bnull - 12-3-2026 at 02:44

Visit a doctor and get a prescription. Your memory issues have other possible causes that a homebrew lithium salt won't solve. You're not an M.D., are you?

Don't trust internet searches with your health.