Sciencemadness Discussion Board


Baphomet - 19-6-2011 at 00:31

Nitroxyl would be an interesting compound to study, but nitroxyl donors (e.g. Piloty's acid) are expensive.

I've got a couple of ideas for methods to generate nitroxyl using reagents that are easy to obtain, but I'm not sure how feasible they are. If anyone could take a look it'd be appreciated!

From this thread: there is a reference to an interesting journal article called 'Catalytic oxidation of ammonia' (

The article states:

The kinetics of ammonia oxidation over oxides of manganese, cobalt, copper, iron and vanadium have been studied. The proposed reaction mechanism involves oxygen adsorption (oxidation of the catalyst surface) and reduction of the surface with ammonia to form the reaction products. The latter step consists of several stages involving the intermediate formation of nitroxyl and imide species. The interaction of imide with nitroxyl leads to nitrogen while the reaction between two nitroxyls results in nitrous oxide.

Would there be a way to skew the reaction towards more nitroxyl and less imide? Perhaps if the amount of oxygen is kept low? It might be as simple as passing the air/ammonia mixture over heated iron oxide..

Also I wonder if there is a way to capture the imide species so that it doesn't react with HNO?

Another idea was to produce NO by reacting nitric acid with copper, but I'm not sure how to turn NO into HNO/NO-. Perhaps form a metal nitrosyl complex and then isolate it and react it under some sort of condition that would release nitroxyl?

Baphomet - 19-6-2011 at 00:56

Direct reduction of NO by Zn/HCl is probably out (potential +0.76V), and it looks like a stronger reducing agent would be needed (which I don't have :()