I'm interested in making a bit of sodium triacetoxyborohydride for future reductive aminations (just got a 1st yr uni organic chem book), and I was
just wondering how I could go about this? I saw something about dissolving it in ethyl acetate and adding a few moles of glacial acetic, but I did not
find anything more, as the synthesis was incomplete. Google hasn't turned up anything else.
I'm not sure if this is feasible, but any suggestions would be great.
I've just gotten back into organic chemistry, which I almost dropped a year ago. I was doing pyrotechnics and energetic materials, but I decided to
stop for want of expensive safety equipment. Now that I'm doing more complex chemistry in high school, I know I should definitely take this as part of
my career.
ethylacetate is a great solvent for stabuchiacon - 19-7-2011 at 18:51
hm, I meant triacetoxyborohydride, this looks like it's for acyloxyborohydrides... was there a bit of a mix up here? triacetoxyborohydride is only
mentioned once in the whole document.tmb - 19-7-2011 at 22:57
It is mentioned many times. If you must isolate it, here is how:
NaBH4 (0.1 mol.) was added portionwise to a solution of acetic acid (0.33 mol.) in dry benzene (1 l.), the temperature being kept at 20C. After
hydrogen evolution, the precipitate was rapidly collected by suction, washed with diethyl ether, and dried under vacuum.
[Edited on 20-7-2011 by tmb]Nicodem - 20-7-2011 at 12:29
I'm interested in making a bit of sodium triacetoxyborohydride for future reductive aminations (just got a 1st yr uni organic chem book), and I was
just wondering how I could go about this?
You could go about this by UTFSE. The most basic skill of every good researcher is the use of TFSE.
PS: Open referenceless threads only in the Beginnings section, where this one is being moved.
